7 clinical trials found.
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A SINGLE-CENTER OBSERVATIONAL LONGITUDINAL STUDY ON THE EFFECT OF SLOW WAVE SLEEP (SWS) CHARACTERISTICS AND RACE AND ETHNICITY ON AMYLOID BURDEN (A MARKER OF ALZHEIMER S DISEASE RISK) AMONG COGNITIVELY NORMAL ELDERLY.
African-Americans (AAs) have an increased prevalence of both Alzheimer’s disease (AD) and vascular risk factors for AD such as diabetes and hypertension when compared ...Phase N/A
TRIAL ROLE: Co-Investigator
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SLEEP AGING AND RISK FOR ALZHEIMER S (RESUBMISSION-1)
Age-related sleep changes and common sleep disorders like obstructive sleep apnea (OSA) may increase amyloid burden and represent risk factors for cognitive decline. In this ...Phase N/A TRIAL ROLE: Sub Investigator
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Investigating the Temperature Dependence of Age-related Tau Pathology Relevant to Early Alzheimer's Disease
This is a cross-sectional study in 100 older adults (n = 100, 50 female, 60–80 years) who are cognitively normal (n = 70) or have mild ...Phase N/A TRIAL ROLE: Co-Investigator
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Brain Effects of Lifetime Racial/Ethnic Discrimination on the LC-NE Function and the Risk for Alzheimer's Disease
The current biomarker classification system (i.e., the ATN model) may not fully account for racial disparity and can’t explain the increased prevalence in ...Phase N/A TRIAL ROLE: Sub Investigator
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Using a Health Disparity Research Framework to examine mechanisms linking Obstructive Sleep Apnea with higher Alzheimer s disease risk in older Blacks/African-Americans
Blacks/African-Americans (blacks) have two times the risk of developing Alzheimer’s disease (AD) compared to non-Hispanic whites (whites), in part attributable to the higher ...Phase N/A TRIAL ROLE: Sub Investigator
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Effects of Successful OSA TreatmENT on Memory and AD BIomarkers in Older AduLts (ESSENTIAL)
The prevalence of Alzheimer disease (AD) is high and projected to increase. Further, epidemiological data suggests that ~15% of AD risk may be attributed to ...Phase
TRIAL ROLE: Co-Investigator
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Treatment Of OSA On Sleep-Dependent Memory And Blood Biomarkers In Black Study Participants
The purpose of this research study is assess whether treating sleep apnea affects memory and other brain-related health factors related to Alzheimer’s disease and ...Phase N/A TRIAL ROLE: Sub Investigator
