11 clinical trials found.
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A Phase 1 Multicenter Open-Label Study Of CC-97540 (BMS-986353) CD19-Targeted Nex-T Chimeric Antigen Receptor (CAR) T Cells in Participants with Severe Refractory Autoimmune Diseases: Systemic Lupus Erythematosus Idiopathic Inflammatory Myopathy or Systemic Sclerosis
SLE disease activity results in accumulation of tissue and organ damage (eg, nephritis, multisystem organ failure, and central nervous disease) that contributes to morbidity and ...Phase
TRIAL ROLE: Principal Investigator
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A Multicenter Randomized Double-Blind Placebo-Controlled Non-inferiority Crossover Study Evaluating the Safety and Immunogenicity of the Herpes Zoster Subunit Vaccine in Patients with Systemic Lupus Erythematosus
This randomized, double-blind, placebo-controlled, non-inferiority crossover study will evaluate the HZ/su vaccine in SLE patients in order to evaluate safety and immunogenicity in patients ...Phase
Accepts Healthy Volunteer
TRIAL ROLE: Principal Investigator
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The IRIS trial: A clinical trial for people living with active lupus nephritis (LN)
IRIS is looking to see if a new FDA-approved therapy called SAPHNELO® may be effective in treating people with active LN. SAPHNELO® is the brand ...Phase
TRIAL ROLE: Principal Investigator
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Rheumatology SAMPLE (Specimen And Matched Phenotype Linked Evaluation) Registry and Biorepository
In this research proposal, we will develop a clinical registry containing information related to the patient’s ethnicity, race, gender, age, medications, specific disease or ...Phase N/A Accepts Healthy Volunteer
TRIAL ROLE: Sub Investigator
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Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly
Fetal complete (i.e., third degree) atrioventricular block (AVB), identified in the 2nd trimester of pregnancy in an otherwise normally developing heart, is almost universally ...Phase
TRIAL ROLE: Sub Investigator
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An Evaluation of Home Urinalysis Testing for Systemic Lupus Erythematosus (SLE) Patients at Elevated Risk for Developing Lupus Nephritis: A Pilot Stage and Randomized Controlled Study
The purpose of this study is to find out if at-home urine testing in between doctor’s visits is a feasible approach for lupus patients ...Phase N/A TRIAL ROLE: Sub Investigator
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Lupus Omics Cutaneous Kidney Investigative Team: Skin Project 1 and Skin Project 2
Cutaneous lupus erythematosus (CLE) includes three main subsets: acute CLE (ACLE), subacute CLE (SCLE) and chronic CLE (CCLE), the latter including discoid lupus erythematosus (DLE ...Phase N/A TRIAL ROLE: Sub Investigator
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METRO Lupus Consortium
The purpose of this study is to learn more about patients with lupus ("systemic lupus erythematosus" or "SLE") who may have injury to their kidney ...Phase N/A TRIAL ROLE: Sub Investigator
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Lupus Omics Cutaneous Kidney Investigative Team: Kidney Project 1
The purpose of this study is to learn more about patients with lupus (“systemic lupus erythematosus” or “SLE”) who may have injury to their kidney ...Phase N/A TRIAL ROLE: Sub Investigator
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A Phase III Randomized Double-Blind Placebo-Controlled Non-Inferiority Multi-Center Study of the Effects of Stopping Hydroxychloroquine in Elderly Lupus Disease
This study aims to develop evidence-based protocols for managing older patients with systemic lupus erythematosus (SLE), a topic that has been largely overlooked. Hydroxychloroquine (HCQ ...Phase
TRIAL ROLE: Sub Investigator
