8 clinical trials found.
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Open Label Single Arm Pilot Study to Assess Feasibility and Safety of Iron Repletion with Feraheme in Iron Deficient Patients with durable Ventricular Assist Device support
The purpose of this study is to test the feasibility of an intravenous (IV, given through a vein) medicine (Ferumoxytol) to replace iron in patients ...Phase
Interventional
TRIAL ROLE: Sub Investigator
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TRiluminate - treatment of tricuspid regurgitation
The purpose of this research study is to compare the performance of the investigational tricuspid valve repair system plus optimal drug therapy with optimal drug ...Phase N/A Interventional
TRIAL ROLE: Sub Investigator
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Transcatheter Mitral Valve Replacement with the Medtronic Intrepid TMVR System in patients with severe symptomatic mitral regurgitation APOLLO Trial
The purpose of this study is to see how safe and effective an investigational device called Intrepid TMVR system is for mitral regurgitation. TMVR stands ...Phase N/A Interventional
TRIAL ROLE: Sub Investigator
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Edwards PASCAL TrAnScatheter Mitral Valve RePair System Pivotal Clinical Trial (CLASP IID): A prospective multicenter randomized controlled pivotal trial to evaluate the safety and effectiveness of transcatheter mitral valve repair with the Edwards PASCAL Transcatheter Mitral Valve Repair System compared to Abbott MitraClip in patients with degenerative mitral regurgitation (DMR)
The goal of this study is to assess the safety and performance of the PASCAL System in patients with symptomatic degenerative mitral regurgitation (DMR) who ...Phase N/A Interventional
TRIAL ROLE: Sub Investigator
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Hemodynamic-Guided Management of Heart Failure (CIP-10170)
The purpose of this research study is to see if a heart pressure sensor called the CardioMEMS™ PA Sensor (referred to as “the device”) within ...Phase N/A TRIAL ROLE: Sub Investigator
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A Phase 3 Global Double-Blind Randomized Placebo-Controlled Study to Evaluate the Efficacy and Safety of ION-682884 in Patients with Transthyretin-Mediated Amyloid Cardiomyopathy
The purpose of this study is to evaluate the safety of ION-682884 and determine if it can help people with cardiomyopathy.ION-682884 is an investigational ...Phase
Interventional
TRIAL ROLE: Sub Investigator
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A Double-blind Randomized Placebo-controlled Multicenter Study to Assess the Effect of Omecamtiv Mecarbil on Exercise Capacity in Subjects with Heart Failure with Reduced Ejection Fraction and Decreased Exercise Tolerance
The purpose of this study is to find out more about the effects of an investigational drug called omecamtiv mecarbil (OM), when given to people ...Phase
Interventional
TRIAL ROLE: Sub Investigator
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Evaluation of the Safety and Performance of Medtronic Intrepid Transcatheter Mitral Valve Replacement System with Transfemoral Transseptal Access in Patients with Severe Symptomatic Mitral Regurgitation
This study is testing an investigational device for mitral regurgitation without the need for open heart surgery. The device is called the IntrepidTM Transcatheter Mitral ...Phase N/A Interventional
TRIAL ROLE: Sub Investigator
