9 clinical trials found.
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COVID-19 - Emergency IND
This is a prospective multicenter registry with an embedded open-label randomized clinical trial to determine the effects of standard of care treatment vs. standard of ...Phase
Interventional
TRIAL ROLE: Sub Investigator
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Open Label Single Arm Pilot Study to Assess Feasibility and Safety of Iron Repletion with Feraheme in Iron Deficient Patients with durable Ventricular Assist Device support
The purpose of this study is to test the feasibility of an intravenous (IV, given through a vein) medicine (Ferumoxytol) to replace iron in patients ...Phase
Interventional
TRIAL ROLE: Sub Investigator
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TrAnScatheter Valve RePair System in Tricuspid Regurgitation (CLASP TR) Early Feasibility Study
This study will evaluate the safety and performance of the Edwards PASCAL Transcatheter Valve Repair System (hereinafter referred to as the PASCAL System) in patients ...Phase N/A Interventional
TRIAL ROLE: Sub Investigator
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TRiluminate - treatment of tricuspid regurgitation
The purpose of this research study is to compare the performance of the investigational tricuspid valve repair system plus optimal drug therapy with optimal drug ...Phase N/A Interventional
TRIAL ROLE: Sub Investigator
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Transcatheter Mitral Valve Replacement with the Medtronic Intrepid TMVR System in patients with severe symptomatic mitral regurgitation APOLLO Trial
The purpose of this study is to see how safe and effective an investigational device called Intrepid TMVR system is for mitral regurgitation. TMVR stands ...Phase N/A Interventional
TRIAL ROLE: Sub Investigator
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A Phase 3 Multinational Randomized Placebo-controlled Study of ARRY-371797 in Patients with Symptomatic Dilated Cardiomyopathy Due to a Lamin A/C Gene Mutation
This multinational Phase 3 study will evaluate the efficacy, safety and PK following treatment with ARRY-371797 compared with placebo (1:1 randomization) in at least ...Phase
Interventional
TRIAL ROLE: Sub Investigator
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Edwards PASCAL TrAnScatheter Mitral Valve RePair System Pivotal Clinical Trial (CLASP IID): A prospective multicenter randomized controlled pivotal trial to evaluate the safety and effectiveness of transcatheter mitral valve repair with the Edwards PASCAL Transcatheter Mitral Valve Repair System compared to Abbott MitraClip in patients with degenerative mitral regurgitation (DMR)
The goal of this study is to assess the safety and performance of the PASCAL System in patients with symptomatic degenerative mitral regurgitation (DMR) who ...Phase N/A Interventional
TRIAL ROLE: Sub Investigator
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Hemodynamic-Guided Management of Heart Failure (CIP-10170)
The purpose of this research study is to see if a heart pressure sensor called the CardioMEMS™ PA Sensor (referred to as “the device”) within ...Phase N/A TRIAL ROLE: Sub Investigator
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A Phase 3 Global Double-Blind Randomized Placebo-Controlled Study to Evaluate the Efficacy and Safety of ION-682884 in Patients with Transthyretin-Mediated Amyloid Cardiomyopathy
The purpose of this study is to evaluate the safety of ION-682884 and determine if it can help people with cardiomyopathy.ION-682884 is an investigational ...Phase
Interventional
TRIAL ROLE: Sub Investigator
