12 clinical trials found.
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Anti-viral therapy in Alzheimer's disease
This study is being conducted to evaluate if the generic anti-viral medication, valacyclovir, is helpful in treating Alzheimer's disease in patients who have tested positive ...Phase
TRIAL ROLE: Principal Investigator
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Alzheimer s Disease Research Center
The purpose of this study is to study the diagnosis, clinical course, risk factors, causes and treatment of cognitive impairment in aging, Alzheimer’s disease ...Phase N/A
Accepts Healthy Volunteer
TRIAL ROLE: Principal Investigator
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Phase 3 trial of oral ALZ-801 in Early AD patients who are homozygous for the epsilon 4 variant of the Apolipoprotein E gene (APOE4/4)
The purpose of this study is to determine if the study drug called ALZ-801 is safe, if it is well tolerated (how your body reacts ...Phase
TRIAL ROLE: Principal Investigator
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A Placebo-Controlled Double-blind Parallel-group 18 Month Study To Confirm Safety and Efficacy of BAN2401 in Subjects With Early Alzheimer s Disease
This is a research study to evaluate the safety and effectiveness of the study drug BAN2401.BAN2401 is given by an intravenous infusion, which is ...Phase
TRIAL ROLE: Sub Investigator
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Risk factors for sudden unexplained death in epilepsy (SUDEP)
The purpose of this multi-site study is to build a research registry – the “North American SUDEP Registry (NASR)” to assess the risk factors and pathophysiologic ...Phase
Accepts Healthy Volunteer
TRIAL ROLE: Sub Investigator
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Alzheimer's Disease Neuroimaging Initiative 3 (ADNI3) Protocol: ATRI-001
Subjects who are currently participating in the ADNI-2 research study as well as new subjects are invited to another study. ADNI-w was designed to look ...Phase N/A Accepts Healthy Volunteer
TRIAL ROLE: Sub Investigator
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Developing advanced blood-brain barrier permeability imaging for early AD
Aging is the primary risk factor in aging-related dementia. An important initiating factor for the development and progression of cognitive impairment is disruption of the ...Phase
Accepts Healthy Volunteer
TRIAL ROLE: Sub Investigator
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In vivo insights of small vessel changes with age using ultra-small-superparamagnetic-iron-oxide (USPIO)-enhanced MRI
The purpose of this research study is to investigate a new magnetic resonance imaging (MRI) method that could provide new fundamental insights to a more ...Phase N/A Accepts Healthy Volunteer
TRIAL ROLE: Sub Investigator
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Sleep Aging and Risk for Alzheimer's
Age-related sleep changes and common sleep disorders like obstructive sleep apnea (OSA) may increase amyloid burden and represent risk factors for cognitive decline. In this ...Phase N/A Accepts Healthy Volunteer
TRIAL ROLE: Co-Investigator
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A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)
This is a research study to evaluate the safety and effectiveness of the study drug donanemab to see if it will help slow the mental ...Phase
TRIAL ROLE: Sub Investigator
