3 clinical trials found.
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MAGNITUDE: A Phase 3 Multinational Multicenter Randomized Double-Blind Placebo-Controlled Study to Evaluate the Efficacy and Safety of NTLA-2001 in Participants with Transthyretin Amyloidosis with Cardiomyopathy (ATTR-CM)
This trial is recruiting patients with a condition known as Transthyretin (TTR) Amyloidosis with Cardiomyopathy or ATTR-CM. In individuals with this condition, the heart muscle ... -
Autonomic dysfunction and peripheral neuropathy in patients with cardiac ATTR amyloidosis
This study will aim to determine the most reliable and cost-efficient studies for diagnosing peripheral polyneuropathy and autonomic neuropathy in patients with ATTR amyloidosis who ... -
A Phase 3 Randomized Multicenter Double-Blind Placebo-Controlled Study of Acoramidis for Transthyretin Amyloidosis Prevention in the Young (ACT-EARLY Trial)
The purpose of this research study is to see if an investigational drug, acoramidis (AG10), is safe and effective in preventing or delaying symptoms of ...
TRIAL ROLE: Sub Investigator