2 clinical trials found.
-
A pragmatic trial to evaluate the intermediate-term effects of early aggressive versus escalation therapy in people with multiple sclerosis
The TREAT-MS trial (TRaditional versus Early Aggressive Therapy for MS) is a pragmatic, randomized controlled trial that has two primary aims: 1) to evaluate, jointly ... -
Mechanistic basis for impaired B cell depletion after anti-CD20 treatment of African American with neuro-inflammatory disorders
Infusable anti-CD20 (aCD20) therapies (rituximab, ocrelizumab) emerged as the mainstay of treatment in multiple sclerosis and related disorders (MSARD). Standard, every-6-month dosing of aCD20 achieves ...