Displaying 549 (all) recruiting clinical trials.
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Percutaneous MitraClipTM Device or Surgical Mitral Valve REpair in PAtients with PrImaRy MItral Regurgitation who are Candidates for Surgery (REPAIR-MR)
REPAIR-MR is a prospective, multicenter, randomized, controlled, clinical trial of the MitraClip™ device in subjects with severe primary MR whose mitral valve has been determined ...Phase N/A
Interventional
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NAUTIKA1: A Multicenter Phase II Neoadjuvant and Adjuvant Study of Multiple Therapies in Biomarker-Selected Patients with Resectable Stages IB-III Non-Small Cell Lung Cancer
Study ML41591, is an umbrella trial that will evaluate the efficacy and safety of targeted therapies in patients with resectable Stage IA2, IB, II, IIIA ...Phase
Interventional
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Site for AAML1831: A phase 3 randomized trial for patients with de novo AML comparing standard therapy including gemtuzumab ozogamicin GO to CPX-351 with GO and the addition of the FLT3 inhibitor gilteritinib for patients with FLT3 mutations
Site for This phase III trial compares standard chemotherapy to therapy with CPX-351 and/or gilteritinib for patients with newly diagnosed acute myeloid leukemia with ...Phase
Interventional
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Serologic Testing and Genomic Analysis of Autoimmune Immune-Mediated and Rheumatic Patients with COVID-19 (SAGA)
This is a prospective cohort study involving all subjects enrolled in the Web-based Assessment of Autoimmune, Immune-Mediated, and Rheumatic Patients during the COVID-19 Pandemic (WARCOV ...Phase N/A
Non-Interventional
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Impact of Weight Loss in Patients with Hypertrophic Cardiomyopathy
This is an observational imaging study to evaluate the cardiac effects of weight loss in obese patients with a BMI >=30 with a confirmed diagnosis ...Phase N/A Non-Interventional
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Gut microbiome alterations as a mechanism of immune dysregulation in new-onset refractory status epilepticus (NORSE)
We will perform a prospective, observational cohort study, with biospecimen collection, of NORSE subjects and subjects with status epilepticus of known cause (e.g. epilepsy ...Phase N/A Non-Interventional
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Site for A 78-week trial comparing the effect and safety of once weekly insulin icodec and once daily insulin glargine 100 units/mL both in combination with non-insulin anti-diabetic treatment in insulin na ve subjects with type 2 diabetes
Site for To demonstrate the effect on glycaemic control of once weekly insulin 287, with or without non-insulin anti-diabetic drugs, in insulin naïve subjects with ...Phase
Interventional
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NEW YORK OSTEOARTHRITIS HAND COHORT
This is an observational, longitudinal registry of patients with hand osteoarthritis (HOA) that broadly aims to assess the clinical spectrum, risk factors, and identify possible ...Phase N/A Non-Interventional
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A Phase 1b Study of Nivolumab in Patients with Autoimmune Disorders and Advanced Malignancies (AIM-NIVO)
Nivolumab will be investigated at the Food and Drug Administration (FDA)-approved dose of 480 mg intravenous (IV) every 4 weeks until unacceptable toxicity, disease ...Phase
Interventional
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A Randomized controlled study of a health literacy-informed technology-based approach to support safe medication use by parents after discharge of infants from the neonatal intensive care unit
This is a randomized controlled study of parents of children to be discharged from the neonatal intensive care unit at Bellevue and Elmhurst hospitals. A ...Phase N/A Interventional
