Displaying 536 (all) recruiting clinical trials.
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Combined Phase 3 Double-blind Randomized Placebo-Controlled Studies Evaluating the Efficacy and Safety of Filgotinib in the Induction and Maintenance of Remission in Subjects with Moderately to Severely Active Crohn s Disease
The purpose of this study is to see if filgotinib is effective and safe in treating people with moderate to severe Crohn’s disease. The ...Phase
Interventional
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Edwards PASCAL TrAnScatheter Mitral Valve RePair System Pivotal Clinical Trial (CLASP IID): A prospective multicenter randomized controlled pivotal trial to evaluate the safety and effectiveness of transcatheter mitral valve repair with the Edwards PASCAL Transcatheter Mitral Valve Repair System compared to Abbott MitraClip in patients with degenerative mitral regurgitation (DMR)
The goal of this study is to assess the safety and performance of the PASCAL System in patients with symptomatic degenerative mitral regurgitation (DMR) who ...Phase N/A Interventional
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Measurement of Thrombelastography as an alternative means to guide blood product use before invasive procedures in cirrhosis with severe coagulopathy: An observational study
The purpose of this study is to test the use of a blood test known as thromboelastography (TEG). This study will help us see if ...Phase N/A
Non-Interventional
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Ferric Carboxymaltose to Improve Skeletal Muscle Metabolism in Heart Failure Patients with Functional Iron Deficiency
The purpose of this study is to better understand how body levels of iron affect the ability to exercise in patients with heart failure. Heart ...Phase
Interventional
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A Phase 3 Multinational Randomized Placebo-controlled Study of ARRY-371797 in Patients with Symptomatic Dilated Cardiomyopathy Due to a Lamin A/C Gene Mutation
This multinational Phase 3 study will evaluate the efficacy, safety and PK following treatment with ARRY-371797 compared with placebo (1:1 randomization) in at least ...Phase
Interventional
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CHARM: Glibenclamide for Large Hemispheric Infarction Analyzing mRS and Mortality. A Multicenter Double-Blind Placebo-Controlled Randomized Parallel-Group Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 for Severe Cerebral Ed
This is a Phase 3 study, which means that BIIB093 (study drug) has already been investigated in previous clinical research studies with a small number ...Phase
Interventional
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A Prospective International Hip Dysplasia Registry with Follow-up to Skeletal Maturity: An Analysis of Risk Factors Screening Practices and Treatment Outcomes
The purpose of this study is to develop a general prospective registry that includes all elements of the DDH spectrum, from mild dysplasia of a ...Phase N/A Non-Interventional
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AWARE II (AWAreness during REsuscitation) - A Multi-Centre Observational Study of the Relationship between the Quality of Brain Resuscitation and Consciousness Neurological Functional and Cognitive Outcomes following Cardiac Arrest
The purpose of this study is to determine whether clinical measures to improve resuscitation in patients experiencing cardiac arrest (a stopped heart) leads to increased ...Phase N/A Non-Interventional
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A single arm open-label multicenter phase II study of 177Lu-DOTATATE radionuclide in adults with progressive or high-risk meningioma
The purpose of this research study is to test whether Lutathera® (177Lu-DOTATATE) is effective (how well something works) at stopping the growth of meningiomas. This ...Phase
Interventional
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Participation in studies of other experimental drugs or devices within 30 days prior to enrollment in this study
The purpose of this study is to gather information on how well the 3D ICE AcuNav ultrasound is able to visualize the heart during the ...Phase N/A Non-Interventional
