Displaying 18 (all) recruiting clinical trials.
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An Open Label Long-term Extension study to investigate the safety of PF-06823859 Administered to Adult Participants with Active Dermatomyositis (C0251008)
The purpose of this study (C0251008) is to evaluate the long-term safety, and effectiveness of PF06823859 (active study drug) in adult participants with dermatomyositis (DM ...Phase
Interventional
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Targeting Hyaluronan Accumulation Through Exercise in T2DM
The purpose of this study is to examine the effects of exercise on hyaluronan (HA) accumulation in calf muscles. HA is seen in skeletal muscle ...Phase
Interventional
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A Multicenter Randomized Double-Blind Parallel-Group Study to Assess the Efficacy and Safety of Oral Etrasimod as Induction and Maintenance Therapy for Moderately to Severely Active Crohn s Disease
The purpose of this study is to assess an investigational drug called etrasimod (also referred to as the “study drug”) in the treatment of Crohn ...Phase
Interventional
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A Phase II/III randomized study of R-miniCHOP with or without oral azacitidine (CC-486) in participants age 75 years or older with newly diagnosed diffuse large B cell lymphoma Grade IIIb Follicular Lymphoma transformed lymphoma and high-grade B-cell lymphomas with MYC and BCL2 and/or BCL6 rearrangements
The purpose of the study is to evaluate the study drug CC-486 (oral azacitidine) plus the standard drug therapy that fights cancer cells for patients ...Phase
Interventional
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A Phase 2/3 Randomized Open-Label Study of Maintenance GRT-C901/GRT-R902 A Neoantigen Vaccine in Combination with Immune Checkpoint Blockade for Patients with Metastatic Colorectal Cancer
The purpose of the study is to demonstrate clinical efficacy and characterize the clinical activity relating to the maintenance therapy with GRT-C901/GRT-R902 in combination ...Phase
Interventional
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RANDOMIZED PHASE II/III TRIAL OF SENTINEL LYMPH NODE BIOPSY VERSUS ELECTIVE NECK DISSECTION FOR EARLY-STAGE ORAL CAVITY CANCER
The purpose of the study is to compare Elective Neck Dissection (END) and Sentinel Lymph Node (SLN) Biopsy in terms of shoulder related-quality of life ...Phase
Interventional
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The use of cannabidiol (CBD) in pain reduction for knee osteoarthritis. A Double-Blind Randomized Control Study
The purpose of this study is to see if cannabidiol (CBD) orally dissolving tablets (ODTs) can lessen pain needed in people with knee osteoarthritis. CBD ...Phase
Interventional
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A Randomized Double-Blind Placebo-Controlled Dose Escalation and Verification Clinical Study to Assess the Safety and Efficacy of Pulsed Inhaled Nitric Oxide (iNO) in Subjects at Risk of Pulmonary Hypertension associated with Pulmonary Fibrosis on Long Term Oxygen Therapy (Part 1 and Part 2)
The purpose of this study is to determine if the study drug, inhaled nitric oxide (iNO), when given and breathed through an investigational study device ...Phase
Interventional
