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A Phase 2 multicenter randomized double-blind placebo-controlled study to assess the efficacy safety and tolerability of AVP-786 (deudextromethorphan hydrobromide [d6-DM]/quinidine sulfate [Q]) for the treatment of neurobehavioral disinhibition including aggression agitation and irritability in patients with traumatic brain injury (TBI)
Symptoms associated with TBI such as physical and verbal aggression, agitation and irritability are problematic, can be difficult to manage, can be disruptive, and can ...Phase
Interventional
Accepts Healthy Volunteer
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Study to Optimize Immune Coverage of SARS-CoV-2 Existing and Emerging Variants COVAIL Booster Study
The purpose of this research is to test additional vaccine booster shots that use different vaccine types and/or variant spikes to see if these ...Phase
Interventional
Accepts Healthy Volunteer
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Study to Optimize Immune Coverage of SARS-CoV-2 Existing and Emerging Variants COVAIL Booster Study
The purpose of this research is to test additional vaccine booster shots that use different vaccine types and/or variant spikes to see if these ...Phase
Interventional
Accepts Healthy Volunteer
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A Multi-Center Randomized Double-blind Placebo-controlled Dose-finding Study to Evaluate the Safety Tolerability Pharmacokinetics and Pharmacodynamics of CK-3773274 in Adults with Symptomatic Hypertrophic Cardiomyopathy
Some people with HCM have obstructive HCM (oHCM) and other participants have non-obstructive HCM (nHCM). HCM is a condition in which the heart muscle becomes ...Phase
Interventional
