139 "Healthy volunteers" clinical trials found.
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Reduction in spread of excitation as predictor of multi-channel spectral resolution
Despite the impoverished information provided by a cochlear implant (CI), patients are unable to use all of the information provided by the CI speech processor ...Phase N/A
Non-Interventional
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SLEEP AGING AND RISK FOR ALZHEIMER S (RESUBMISSION-1)
Age-related sleep changes and common sleep disorders like obstructive sleep apnea (OSA) may increase amyloid burden and represent risk factors for cognitive decline. In this ...Phase N/A Non-Interventional
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Novel Coding Strategies for Children with Cochlear Implants
Prior to the onset of deafness, the auditory brain of post-lingually deafened adults develops in response to a rich complement of spectral, temporal, and intensity ...Phase N/A
Interventional
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Site for WUH TrialNet: NATURAL HISTORY STUDY OF THE DEVELOPMENT OF TYPE 1 DIABETES
Site for The TrialNet Natural History Study of the Development of T1D is divided into Screening and Monitoring stages. Each stage will require separate informed ...Phase N/A Non-Interventional
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Impact of time restricted feeding in obese subjects undergoing a low-calorie diet
The impact of circadian rhythms appear to impact various biologic mechanisms including sleep, nutrition, and physical activity. We wish to understand the impact of timing ...Phase N/A Interventional
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A single-center longitudinal study of the diagnosis clinical course risk factors causes and treatment of cognitive impairment in aging Alzheimer s disease (AD) and related disorders
The purpose is to study the diagnosis, clinical course, risk factors, causes and treatment of cognitive impairment in aging, Alzheimer’s disease (AD) and related ...Phase N/A Non-Interventional
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Edwards PASCAL TrAnScatheter Valve RePair System Pivotal Clinical Trial (CLASP IID/IIF): A prospective multicenter randomized controlled pivotal trial to evaluate the safety and effectiveness of transcatheter mitral valve repair with the Edwards PASCAL Transcatheter Valve Repair System compared to Abbott MitraClip in patients with mitral regurgitation
This is a prospective, multicenter, randomized, parallel-group study to compare the safety and effectiveness of the PASCAL System to the MitraClip System for reduction of ...Phase N/A Interventional
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Investigating auditory processing in the users of auditory brainstem and cochlear implants
This is a basic investigational research study conducted with hearing impaired adults and children who use cochlear implant or auditory brainstem implant (ABI) devices. The ...Phase N/A Non-Interventional
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A computational approach to optimal deactivation of cochlear implant electrodes
The goal of the present study is to use computationally driven models of speech understanding in CI users to guide the search for which combination ...Phase N/A Interventional
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CP-CGMH: Care Partner-Assisted Diabetes Self-Management Through Linking Continuous Glucose Monitoring with Mobile Health: Improving Outcomes for Older Adults with Mild Cognitive Impairment
The purpose of this study is to examine the acceptability of continuous glucose monitoring (CGM) and identify the key domains of a future care partner-assisted ...Phase
Interventional
