164 "Healthy volunteers" clinical trials found.
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A Phase 1 Randomized Observer-Blind Study to Evaluate the Safety And Tolerability of a Vaccine Candidate Against Respiratory Syncytial Virus in Healthy Individuals 18 Through 49 Years of Age
The purpose of this study is to see if a new type of investigational Respiratory Syncytial Virus (RSV) vaccine called “modRNA RSV vaccine” is safe ... -
Prospective NIPT Sample Collection Protocol
This study is being done to develop and validate an investigational noninvasive prenatal test to determine chromosomal anomalies. Pregnant women >10 weeks gestation with positive ... -
Role of the oral cavity in inflammatory bowel disease
The purpose of this investigation is to create a study bank of clinical data, peripheral blood, oral and gut microbiomes, and mucosal pinch biopsy specimens ... -
Person-Centered Quality Measurement and Management in a System for Addictions Treatment in New York State (Project 2)
To drive change, OASAS will invest in a quality measurement and management (QM2) strategy that provides performance feedback to activate leadership and staff of clinics ... -
Investigating the Temperature Dependence of Age-related Tau Pathology Relevant to Early Alzheimer's Disease
This is a cross-sectional study in 100 older adults (n = 100, 50 female, 60–80 years) who are cognitively normal (n = 70) or have mild ... -
Racial diffErences in the aSsociation Of sLow waVe slEep aNd Tau (RESOLVENT II)
This pilot proposal will examine whether racial differences exist in the association between SWS/SWA and in-vivo regional tau-PET signal for a given level of ... -
Race-spEcific regional Tau deposition and role of Obstructive Sleep Apnea (RETOSA)
This proposal will generate pilot data for an R01 application that aims to determine whether Blacks/African Americans (‘blacks’) generally exhibit lower tau-PET signal compared ... -
ALZHEIMER S DISEASE RELATED BIOMARKERS FOLLOWING SARS-COV-2 INFECTION
A prospective, observational, longitudinal cohort study (n=300) of either: SARS-CoV-2 laboratory positive subjects who have new objective cognitive abnormalities within 12 months of SARS-CoV-2 ... -
Mechanisms of rAcial dIfferences in the relatioNship between Obstructive Sleep Apnea and in vivo Tau deposition in the context of AmYloid burden
African-Americans (blacks) have two times the risk of developing Alzheimer’s disease (AD) compared to non-Hispanic whites.1-6 Neuropathological studies show blacks with more mixed ... -
Autoimmune and Autoinflammatory Genetics Study
This is an exploratory natural history protocol that will enroll patients with known or as yet undiagnosed disorders of inflammation. Blood, saliva, hair, nail, or ...