163 "Healthy volunteers" clinical trials found.
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Chronic Pain and Postoperative Cognitive Function in the Elderly: a Prospective Observational Study
To assess the possible interrelation between pre-operative chronic pain and postoperative cognitive dysfunction (POCD) in the elderly, we plan to enroll patients undergoing planned surgery ... -
Development and Piloting of a Family-Centered mHealth-Enhanced Intervention to Promote Caregiving Mastery in Detection Prevention and Management of Delirium Superimposed on Dementia
Delirium superimposed on dementia (DSD) is an acute and serious condition that is common in persons living with dementia (PLWD). Involvement of family caregivers can ... -
Understanding the Lived Experience of Couples Across the Trajectory of Dementia
This multi-site, observational study will focus on the experience of older couples and the impact of Alzheimer's disease or a related dementia on health ... -
Early Signs: digital phenotyping to identify digital biomarkers for predicting burnout and cognitive functioning in ED clinicians
Our overall goal is to enhance the ability to assess and understand the development of burnout amongst ED staff using objective, ecologically valid, economical, and ... -
Models of speech perception by users of auditory neural prostheses-Project 1
The first specific aim of the proposed research is to develop mathematical models of phoneme and word identification for individual CI users. To achieve this ... -
A Prospective multicenter study to examine the influence of repairing the sub-scapularis on outcomes after reverse arthroplasty: A randomized controlled trial.
Determine how repairing the subscapularis vs. not repairing the subscapularis when subjects are implanted with the AltiVate Reverse® Shoulder System for reverse total shoulder arthroplasty ... -
A green activity prescription program for Chinese Americans living with dementia
This study will iteratively develop and test the feasibility and acceptability of a 12-week green prescription program among Chinese American people living with dementia and ... -
Understanding CSF Clearance in Aging and Alzheimer s Brain Through Dynamic Sodium MRI
This study aim to determine: 1) how age affects CSF production, bulk flow, and drainage in the normal brain; 2) the impact of sleep on ... -
Mechanisms and Enhancement of Learning During Sleep
Memory dysfunction represents one of the most common cognitive complaints in patients with epilepsy and significantly impairs quality of life. Our work aims to (1 ... -
A single-center randomized clinical trial to test the efficacy of pharyngeal swallowing exercises (with or without protein supplementation) to build pharyngeal muscular reserve in pre-frail older adults
The swallowing muscles are prone to decreased strength and function as part of the natural aging process which can lead to difficulty swallowing, malnutrition, and ...