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Functional Brain Imaging in Healthy Volunteers and Epilepsy Patients to Study Cognitive Functions
The purpose of this protocol is to learn about scale-free brain activity as well as conscious vs. unconscious processing in the brain. To improve such ... -
A Double-Blind Randomized Placebo-Controlled Study to Assess the Safety Tolerability and Pharmacodynamics of SYNB8802 in Healthy Volunteers and in Patients with Enteric Hyperoxaluria
SYNB8802 (the drug being tested) is a live biotherapeutic (biologicals) being developed as a potential treatment for enteric hyperoxaluria (EH). EH is a condition in ... -
Technical Software Development for Magnetic Resonance Imaging
The objective of this study is to develop software for magnetic resonance imaging (MRI) to improve diagnostic power and image quality. The study includes both ... -
Performance Evaluation of 3D DIXON MRI of Joints
The purpose of this study is to develop a method for faster MRI of joints. This study will test whether this new technique is reliable ... -
Biology of Blood Cells in Healthy Volunteers
The purpose of the study is to investigate signals in your blood that protect against aneurysm formation. An aneurysm is a bulge in a blood ... -
Phlebotomy of Healthy Adults for the Purpose of Evaluation and Validation of Immune Response and Microbiology Assays
The purpose of this study is to create a bank of different types of samples. Some of these samples might be used to develop and ... -
Prospective MRI Evaluation of Control Subjects for Comparison to Patients with Temporal Lobe Epilepsy
This innovative study aims to develop methods for detection of causes of focal epilepsy beyond the limitations of conventional MRI by using diffusion kurtosis analysis ... -
CHORD - CHOlesterol Lowering and Residual Risk in Type 2 Diabetes
The purpose of this study is to investigate why individuals with type 2 diabetes are at increased risk for heart disease and stroke. In this ... -
Effects of Elevated Intraocular Pressure on Lamina Cribrosa
The purpose of this research study is to examine how the lamina cribrosa, a layer of tissue in the back of the eye, responds to ... -
Optical Coherence Domain Reflectometry and Optical Coherence Tomography Measurements of Intraocular Structure
The purpose of the research to evaluate an ophthalmic imaging device called optical coherence tomography (OCT). This device is working like a camera acquiring images ...