158 "Healthy volunteers" clinical trials found.
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Race-spEcific regional Tau deposition and role of Obstructive Sleep Apnea (RETOSA)
This proposal will generate pilot data for an R01 application that aims to determine whether Blacks/African Americans (‘blacks’) generally exhibit lower tau-PET signal compared ...Phase N/A
Non-Interventional
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ALZHEIMER S DISEASE RELATED BIOMARKERS FOLLOWING SARS-COV-2 INFECTION
A prospective, observational, longitudinal cohort study (n=300) of either: SARS-CoV-2 laboratory positive subjects who have new objective cognitive abnormalities within 12 months of SARS-CoV-2 ...Phase N/A Non-Interventional
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Mechanisms of rAcial dIfferences in the relatioNship between Obstructive Sleep Apnea and in vivo Tau deposition in the context of AmYloid burden
African-Americans (blacks) have two times the risk of developing Alzheimer’s disease (AD) compared to non-Hispanic whites.1-6 Neuropathological studies show blacks with more mixed ...Phase
Non-Interventional
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Autoimmune and Autoinflammatory Genetics Study
This is an exploratory natural history protocol that will enroll patients with known or as yet undiagnosed disorders of inflammation. Blood, saliva, hair, nail, or ...Phase N/A Non-Interventional
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Ferumoxytol-enhanced MRI of Cerebrovascular Diseases
The purpose of this research study is to assess new magnetic resonance imaging methods and a new contrast agent for the evaluation of cerebrovascular diseases ...Phase N/A Non-Interventional
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A Phase 2 double-blind placebo-controlled parallel-group study to assess the safety tolerability pharmacokinetics pharmacodynamics and potential efficacy of multiple doses of ONO-2808 in patients with Multiple System Atrophy (MSA)
The purpose of this clinical research study is to look at the safety and tolerability of the investigational study drug, ONO-2808, and whether it works ...Phase
Interventional
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Investigating Dynamic Causes of Dorsal Wrist Pain
This is a prospective cohort study to evaluate for causes of dorsal wrist pain using a Wrist Glove MRI Coil to allow for dynamic imaging ...Phase N/A Interventional
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Non-invasive neurosurgical planning with Random Matrix Theory MRI
The primary focus of this study will be to develop and validate an Radiofrequency (RF) coil-based multimodal Random Matrix Theory (RMT) denoising/reconstruction for brain ...Phase N/A Non-Interventional
