132 "Healthy volunteers" clinical trials found.
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Brain Effects of Lifetime Racial/Ethnic Discrimination on the LC-NE Function and the Risk for Alzheimer's Disease
The current biomarker classification system (i.e., the ATN model) may not fully account for racial disparity and can’t explain the increased prevalence in ...Phase N/A
Non-Interventional
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Technical Development Observational study for Microstructure MRI
Newly developed imaging protocols will conform to scanner safety requirements and any applicable FDA standards. The output of the scanning session will be in the ...Phase N/A Non-Interventional
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Long-acting buprenorphine vs. naltrexone opioid treatments in CJS-involved adults (EXIT CJS)
This study seeks to meaningfully address the U.S. opioid epidemic by comparing the effectiveness of two medications used to treat opioid use disorder, extended-release ...Phase
Interventional
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Single-center observational longitudinal study to identify predictors of progression of joint damage after non-contact rupture of anterior cruciate ligament
Post-traumatic osteoarthritis (PTOA) is a common occurrence after anterior cruciate ligament (ACL) rupture independently of patient treatment, which indicates that early cellular and molecular changes ...Phase N/A Non-Interventional
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Simultaneous Multinuclear Magnetic Resonance Fingerprinting for Data Fusion of Quantitative Structural and Metabolic Imaging
This proposal seeks to perform an observational study, for evaluating a new non-invasive imaging technique that will provide multi-parametric metabolic 3D maps of the living ...Phase N/A Non-Interventional
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Autonomic Modulation in Takotsubo Syndrome
The purpose of this research study is to learn whether slow breathing is beneficial for patients with Takotsubo Syndrome. The RESPeRATE device will be used ...Phase
Interventional
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GUT KIDNEY AXIS IN ENTERIC HYPEROXALURIA - A clinical prospective study of the effects of the microbiome on urinary oxalate in participants with enteric hyperoxaluria fed a moderate oxalate diet
40 subjects with a confirmed diagnosis of IBD or >6 months post-RYGB with a diagnosed USD event or kidney stone on imaging within the past ...Phase
Interventional
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IRON DEFICITS AND THEIR RELATIONSHIP WITH SYMPTOMS AND COGNITION IN PSYCHOTIC SPECTRUM DISORDERS
Psychotic Spectrum Disorders (PSD) are severe mental syndromes associated with significant lifelong impairment and high prevalence. In this proposal we aim to employ non-invasive imaging ...Phase N/A Non-Interventional
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Unpacking the Importance of the Structural Injuries of MTBI
To find imaging biomarkers of injury associated with symptoms in patients with MTBI by discovering the relationship between structural alterations and clinical status including cognition.Phase N/A Non-Interventional
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Integrating financial coaching and smoking cessation coaching for people with low income who smoke: a randomized controlled trial
This study conduct a two-arm, parallel-group randomized controlled trial. We will recruit and randomize 900 smokers (n=450 per arm) to either: (1) Control: Standard ...Phase
Interventional
