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Magnetic Resonance Imaging Evaluation of Normal Heart Function in Men and Women
The purpose of the proposed study is the creation of an initial functional atlas of the normal adult human heart, using data derived with cardiac ... -
Platelet Activity and Vascular Health in System Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a remarkably complex disease that poses several challenges to the clinician, including heterogeneity of presentation, undulating course, and elevated risk ... -
Young Onset Parkinson s disease Subtypes and Pathogenic Mechanisms
Young Onset Parkinson’s disease refers to a -group of patients in which the disease starts earlier in life (before the age of 50 years ... -
Role of the oral cavity in inflammatory bowel disease
The purpose of this investigation is to create a study bank of clinical data, peripheral blood, oral and gut microbiomes, and mucosal pinch biopsy specimens ... -
Investigating the Temperature Dependence of Age-related Tau Pathology Relevant to Early Alzheimer's Disease
This is a cross-sectional study in 100 older adults (n = 100, 50 female, 60–80 years) who are cognitively normal (n = 70) or have mild ... -
Racial diffErences in the aSsociation Of sLow waVe slEep aNd Tau (RESOLVENT II)
This pilot proposal will examine whether racial differences exist in the association between SWS/SWA and in-vivo regional tau-PET signal for a given level of ... -
Race-spEcific regional Tau deposition and role of Obstructive Sleep Apnea (RETOSA)
This proposal will generate pilot data for an R01 application that aims to determine whether Blacks/African Americans (‘blacks’) generally exhibit lower tau-PET signal compared ... -
ALZHEIMER S DISEASE RELATED BIOMARKERS FOLLOWING SARS-COV-2 INFECTION
A prospective, observational, longitudinal cohort study (n=300) of either: SARS-CoV-2 laboratory positive subjects who have new objective cognitive abnormalities within 12 months of SARS-CoV-2 ... -
Ferumoxytol-enhanced MRI of Cerebrovascular Diseases
The purpose of this research study is to assess new magnetic resonance imaging methods and a new contrast agent for the evaluation of cerebrovascular diseases ... -
Investigating Dynamic Causes of Dorsal Wrist Pain
This is a prospective cohort study to evaluate for causes of dorsal wrist pain using a Wrist Glove MRI Coil to allow for dynamic imaging ...