165 "Healthy volunteers" clinical trials found.
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Platelet Activity and Vascular Health in System Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a remarkably complex disease that poses several challenges to the clinician, including heterogeneity of presentation, undulating course, and elevated risk ...Phase N/A
Non-Interventional
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Young Onset Parkinson s disease Subtypes and Pathogenic Mechanisms
Young Onset Parkinson’s disease refers to a -group of patients in which the disease starts earlier in life (before the age of 50 years ...Phase N/A Non-Interventional
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A Phase 1 Randomized Observer-Blind Study to Evaluate the Safety And Tolerability of a Vaccine Candidate Against Respiratory Syncytial Virus in Healthy Individuals 18 Through 49 Years of Age
The purpose of this study is to see if a new type of investigational Respiratory Syncytial Virus (RSV) vaccine called “modRNA RSV vaccine” is safe ...Phase
Interventional
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Role of the oral cavity in inflammatory bowel disease
The purpose of this investigation is to create a study bank of clinical data, peripheral blood, oral and gut microbiomes, and mucosal pinch biopsy specimens ...Phase N/A Non-Interventional
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Person-Centered Quality Measurement and Management in a System for Addictions Treatment in New York State (Project 2)
To drive change, OASAS will invest in a quality measurement and management (QM2) strategy that provides performance feedback to activate leadership and staff of clinics ...Phase N/A Non-Interventional
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Investigating the Temperature Dependence of Age-related Tau Pathology Relevant to Early Alzheimer's Disease
This is a cross-sectional study in 100 older adults (n = 100, 50 female, 60–80 years) who are cognitively normal (n = 70) or have mild ...Phase N/A Interventional
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Racial diffErences in the aSsociation Of sLow waVe slEep aNd Tau (RESOLVENT II)
This pilot proposal will examine whether racial differences exist in the association between SWS/SWA and in-vivo regional tau-PET signal for a given level of ...Phase N/A Non-Interventional
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Race-spEcific regional Tau deposition and role of Obstructive Sleep Apnea (RETOSA)
This proposal will generate pilot data for an R01 application that aims to determine whether Blacks/African Americans (‘blacks’) generally exhibit lower tau-PET signal compared ...Phase N/A Non-Interventional
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ALZHEIMER S DISEASE RELATED BIOMARKERS FOLLOWING SARS-COV-2 INFECTION
A prospective, observational, longitudinal cohort study (n=300) of either: SARS-CoV-2 laboratory positive subjects who have new objective cognitive abnormalities within 12 months of SARS-CoV-2 ...Phase N/A Non-Interventional
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Mechanisms of rAcial dIfferences in the relatioNship between Obstructive Sleep Apnea and in vivo Tau deposition in the context of AmYloid burden
African-Americans (blacks) have two times the risk of developing Alzheimer’s disease (AD) compared to non-Hispanic whites.1-6 Neuropathological studies show blacks with more mixed ...Phase
Non-Interventional
