147 "Healthy volunteers" clinical trials found.
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Technical Software Development on Ultra-Low Field MRI
In this technical developmental study, we aim (i) to evaluate the hypothesis that ultra-low field MRI systems can produce images with meaningful structural and physiological ...Phase N/A
Non-Interventional
Accepts Healthy Volunteer
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Long-acting buprenorphine vs. naltrexone opioid treatments in CJS-involved adults (EXIT CJS)
This study seeks to meaningfully address the U.S. opioid epidemic by comparing the effectiveness of two medications used to treat opioid use disorder, extended-release ...Phase
Interventional
Accepts Healthy Volunteer
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Single-center observational longitudinal study to identify predictors of progression of joint damage after non-contact rupture of anterior cruciate ligament
Post-traumatic osteoarthritis (PTOA) is a common occurrence after anterior cruciate ligament (ACL) rupture independently of patient treatment, which indicates that early cellular and molecular changes ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
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Technical Development observational study for Musculoskeletal (MSK) Magnetic Resonance Imaging
Newly developed MSK imaging protocols will conform to applicable FDA standards and recommendations. The data (images) will be transferred by the scan technologist and downloaded ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
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Technical Development Observational study for multi-nuclear magnetic resonance imaging and spectroscopy
To develop new methodology for multi-nuclear MRI and MRS applications at up to 7T magnet strength. We hypothesize that these new imaging methodologies will allow ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
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Non-invasive neurosurgical planning with Random Matrix Theory MRI
The primary focus of this study will be to develop and validate an Radiofrequency (RF) coil-based multimodal Random Matrix Theory (RMT) denoising/reconstruction for brain ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
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Brain Effects of Lifetime Racial/Ethnic Discrimination on the LC-NE Function and the Risk for Alzheimer's Disease
The current biomarker classification system (i.e., the ATN model) may not fully account for racial disparity and can’t explain the increased prevalence in ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
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Technical Development Observational study for Microstructure MRI
Newly developed imaging protocols will conform to scanner safety requirements and any applicable FDA standards. The output of the scanning session will be in the ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
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A PHASE 1/2 RANDOMIZED STUDY TO EVALUATE THE SAFETY TOLERABILITY IMMUNOGENICITY AND IMMUNOPERSISTENCE OF A CLOSTRIDIOIDES DIFFICILE VACCINE ADMINISTERED IN A 2-DOSE REGIMEN WITH NOVEL ADJUVANTS IN HEALTHY ADULTS
This Phase 1/2 study in adults 65 years of age and older will evaluate the safety and immunogenicity of Clostridioides (formerly Clostridium) difficile vaccine ...Phase
Interventional
Accepts Healthy Volunteer
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Unpacking the Importance of the Structural Injuries of MTBI
To find imaging biomarkers of injury associated with symptoms in patients with MTBI by discovering the relationship between structural alterations and clinical status including cognition.Phase N/A Non-Interventional
Accepts Healthy Volunteer
