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Prodromal and Early Parkinsonism Alpha-Synuclein Study
The purpose of this research study is to collect samples of blood, cerebrospinal fluid (CSF, the fluid that surrounds the brain and spinal cord), skin ... -
Improving Musical Perception in Cochlear Implants
In this multi-site across-subject study, participants will be evaluated with custom written software to test pitch discrimination, the ability to perceive changes in melodic intervals ... -
A Multicenter Prospective Study of Infant Racial/Ethnic Identity and Parent Satisfaction in the NICU
This is a prospective cohort study using a questionnaire with the primary aim of determining whether infant race/ethnicity is accurately designated in the electronic ... -
A SINGLE-SITE OBSERVATIONAL STUDY ON THE ABILITY OF DYNAMIC VASCULAR OPTICAL SPECTROSCOPY TO MONITOR THE HEALTH OF THE CAROTID ARTERY
The purpose of this study is to validate the use of dynamic vascular optical spectroscopy (DVOS) for monitoring oxygen saturation in the carotid artery, we ... -
Computer-Based Cognitive Assessment and Web-Based Work Status Monitoring in Relapsing Multiple Sclerosis Patients Treated with Ozanimod
The purpose of this research is to develop a registry of MS patients treated with Ozanimod that will track and relate measures of cognitive processing ... -
Quantification of Multi-Compartment T1 Relaxation and Magnetization Transfer in Biological Tissue: From Biophysics to Biomarkers for Multiple Sclerosis
The purpose of this study is to evaluate the efficacy of multi-compartment T1 relaxation and magnetization transfer for detecting subtle changes in normal-appearing brain tissue ... -
TSPO-ligand PET imaging in autoimmune epilepsy
The purpose of this study is to use PET/MRI imaging to measure levels of inflammation in the brain of people with autoimmune epilepsy compared ... -
Assessment of glutamate neurotransmission brain bioenergetics and neuroinflammation in major depressive disorder using TSPO PET and MRI
The purpose of this study is to develop PET/MRI techniques for accurate assessment of changes in signal transmission, energy levels and inflammation in the ... -
Cochlear implants and listening effort: the interaction of cognitive and sensory constraints
Hearing impairment is the third most prevalent chronic medical condition among older adults in the United States. Untreated, hearing loss can interfere with effective communication ... -
Magnetic Resonance Imaging of Brain Reorganization and Sensory Substitution Use in Blind Adults
This research aims to examine how using certain types of visual assistive technology can influence behavior and brain activity in visually impaired individuals. The technology ...