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Unpacking the Importance of the Structural Injuries of MTBI
To find imaging biomarkers of injury associated with symptoms in patients with MTBI by discovering the relationship between structural alterations and clinical status including cognition. -
In Vivo Insights of Small Vessel Changes with Age Using Ultra-Small-Superparamagnetic-Iron-Oxide (USPIO)-Enhanced MRI
This proposal seeks to perform an observational study for developing a new imaging tool using an ultra-small-superparamagnetic-iron-oxide (USPIO) contrast agent to characterize age-related microvascular changes ... -
Data-Driven Learning Framework for Fast Quantitative Knee Joint Mapping
We propose a rapid and robust approach for the quantitative multi-compartment assessment of knee cartilage using magnetic resonance imaging without using either exogenous contrast agent ... -
Relationship between the ocular microbiome and pseudoexfoliation syndrome/glaucoma and cataracts
Observational study to determine the microbiome structure of the eye, mouth, and skin of subjects with pseudo exfoliation syndrome, pseudoexfoliation glaucoma, and cataracts before and ... -
Platelet and Endothelial Dysfunction in Psoriasis
Background: Psoriasis is a common chronic inflammatory skin disease associated with an ~50% increased risk of cardiovascular disease (CVD) compared to matched controls. The influence ... -
Chronic Pain and Postoperative Cognitive Function in the Elderly: a Prospective Observational Study
To assess the possible interrelation between pre-operative chronic pain and postoperative cognitive dysfunction (POCD) in the elderly, we plan to enroll patients undergoing planned surgery ... -
Understanding the Lived Experience of Couples Across the Trajectory of Dementia
This multi-site, observational study will focus on the experience of older couples and the impact of Alzheimer's disease or a related dementia on health ... -
Early Signs: digital phenotyping to identify digital biomarkers for predicting burnout and cognitive functioning in ED clinicians
Our overall goal is to enhance the ability to assess and understand the development of burnout amongst ED staff using objective, ecologically valid, economical, and ... -
Models of speech perception by users of auditory neural prostheses-Project 1
The first specific aim of the proposed research is to develop mathematical models of phoneme and word identification for individual CI users. To achieve this ... -
Neural markers of risk for anxiety in infancy
This study will examine associations between brain development and several behavioral risk markers for anxiety. This work will provide novel data on the neurodevelopmental mechanisms ...