154 "Healthy volunteers" clinical trials found.
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A Phase 2 multicenter randomized double-blind placebo-controlled study to assess the efficacy safety and tolerability of AVP-786 (deudextromethorphan hydrobromide [d6-DM]/quinidine sulfate [Q]) for the treatment of neurobehavioral disinhibition including aggression agitation and irritability in patients with traumatic brain injury (TBI)
Symptoms associated with TBI such as physical and verbal aggression, agitation and irritability are problematic, can be difficult to manage, can be disruptive, and can ... -
Functional muscle kinematics in dermatomyositis with diffusion MRI
The purpose of this study is to determine if a combination of advanced MRI techniques can be helpful in the prediction, early diagnosis, and prognosis ... -
Providing hearing assistance to socially isolated older adults in Los Angeles Communities - An Implementation Project
This study will examine hearing impairment in older adults who reside in Los Angeles senior housing communities. Researchers will test hearing and provide residents with ... -
Locus-coeruleus function in normal elderly and AD risk (LEAD)
(S,S)-[11C]Methylreboxetine ((S,S)-[11C]MRB) is a radioligand developed for positron emission tomography (PET) imaging of the brain adrenergic receptors. In ongoing ... -
Alzheimer s Disease Research Center
The purpose of this study is to study the diagnosis, clinical course, risk factors, causes and treatment of cognitive impairment in aging, Alzheimer’s disease ... -
Post-operative Immobilization and Physical Therapy Following Volar Locked Plating for Distal Radius Fractures: Are They Necessary?
The purpose of this study is to see if splinting and formal physical therapy are necessary following surgical fixation (immobilization) of distal radius fractures (broken ... -
A randomized control trial to study the effects of automated physician directed messaging on patient engagement in the digital diabetes prevention program
The purpose of this study is to find out whether messages from providers (doctors) impact how people use diabetes prevention apps. This includes information on ... -
DISCOVER: A single-site double-blind placebo-controlled randomized mechanistic crossover trial to assess the influence of boDy weIght on aSpirin-triggered speCialized prO-resolVing mEdiatoRs
Aspirin is commonly used to prevent heart attacks and strokes in clinical care. Commonly a “baby” aspirin (81mg) is prescribed for this purpose. However, higher ... -
Heterogeneity in OCD and Depression
The purpose of this study is to look at brain functioning in patients with obsessive-compulsive disorder (OCD) or major depressive disorder (depression, MDD). Not all ... -
Treatment for Migraine and Mood (TEAM-M): A Pilot Trial of Mindfulness-based Training Program
The purpose of this research study is to develop and test an intervention designed to improve mood and reduce pain associated with migraine headaches. This ...