126 "Healthy volunteers" clinical trials found.
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Edwards PASCAL TrAnScatheter Valve RePair System Pivotal Clinical Trial (CLASP IID/IIF): A prospective multicenter randomized controlled pivotal trial to evaluate the safety and effectiveness of transcatheter mitral valve repair with the Edwards PASCAL Transcatheter Valve Repair System compared to Abbott MitraClip in patients with mitral regurgitation
This is a prospective, multicenter, randomized, parallel-group study to compare the safety and effectiveness of the PASCAL System to the MitraClip System for reduction of ... -
Investigating auditory processing in the users of auditory brainstem and cochlear implants
This is a basic investigational research study conducted with hearing impaired adults and children who use cochlear implant or auditory brainstem implant (ABI) devices. The ... -
A computational approach to optimal deactivation of cochlear implant electrodes
The goal of the present study is to use computationally driven models of speech understanding in CI users to guide the search for which combination ... -
THE ROLE OF THE MICROBIOME IN MONOZYGOTIC TWINS WITH PSORIASIS AND PSORIATIC ARTHRITIS
We propose a longitudinal study of monozygotic twins discordant for psoriatic disease. Subjects will be characterized with detailed clinical questionnaires in addition to blood, fecal ... -
Mechanisms of Vascular Aneurysms
Our mission is to enable the use of human tissues with outcome data by basic and clinical investigators for research into the biology, causes, prevention ... -
The Role of Residual Hearing in Cochlear Implant Outcomes
Cochlear implants (CIs) have the potential to restore high frequency hearing electrically while maintaining residual low frequency hearing, allowing for simultaneous electric and acoustic listening ... -
Genetic Analysis of Hirschsprung Disease
Hirschsprung disease (HSCR) is a birth defect resulting from the absence of nerve (ganglion) cells in the gastrointestinal tract. Hirschsprung disease has a population incidence ... -
Heart Attack Research Program (HARP)
The Heart Attack Research Program (HARP) is a multi-discipline and mutli-center study that incorporates clinical and basic science and population health to investigate mechanisms of ... -
ADAPTATION TO FREQUENCY-PLACE FUNCTIONS IN COCHLEAR IMPLANT USERS
It is a basic study that will examine adaptation to frequency-place maps in cochlear implant users. The main outcome measures will be measures of speech ... -
Locus-coeruleus function in normal elderly and AD risk (LEAD)
Growing evidence suggests that Alzheimer’s disease (AD) pathological changes begin decades before clinical symptoms and tau abnormalities in the locus coeruleus (LC) can be ...