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Investigating the Temperature Dependence of Age-related Tau Pathology Relevant to Early Alzheimer's Disease
This is a cross-sectional study in 100 older adults (n = 100, 50 female, 60–80 years) who are cognitively normal (n = 70) or have mild ... -
Racial diffErences in the aSsociation Of sLow waVe slEep aNd Tau (RESOLVENT II)
This pilot proposal will examine whether racial differences exist in the association between SWS/SWA and in-vivo regional tau-PET signal for a given level of ... -
Race-spEcific regional Tau deposition and role of Obstructive Sleep Apnea (RETOSA)
This proposal will generate pilot data for an R01 application that aims to determine whether Blacks/African Americans (‘blacks’) generally exhibit lower tau-PET signal compared ... -
ALZHEIMER S DISEASE RELATED BIOMARKERS FOLLOWING SARS-COV-2 INFECTION
A prospective, observational, longitudinal cohort study (n=300) of either: SARS-CoV-2 laboratory positive subjects who have new objective cognitive abnormalities within 12 months of SARS-CoV-2 ... -
Autoimmune and Autoinflammatory Genetics Study
This is an exploratory natural history protocol that will enroll patients with known or as yet undiagnosed disorders of inflammation. Blood, saliva, hair, nail, or ... -
Ferumoxytol-enhanced MRI of Cerebrovascular Diseases
The purpose of this research study is to assess new magnetic resonance imaging methods and a new contrast agent for the evaluation of cerebrovascular diseases ... -
Investigating Dynamic Causes of Dorsal Wrist Pain
This is a prospective cohort study to evaluate for causes of dorsal wrist pain using a Wrist Glove MRI Coil to allow for dynamic imaging ... -
Non-invasive neurosurgical planning with Random Matrix Theory MRI
The primary focus of this study will be to develop and validate an Radiofrequency (RF) coil-based multimodal Random Matrix Theory (RMT) denoising/reconstruction for brain ...