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Role of the Decision-Making Reference Point in Cognition and Psychopathology
Mood disorders are characterized by a tendency to subjectively evaluate objectively positive outcomes in a negative light. A fundamental feature of nearly all standard models ... -
Optimized sodium MR imaging at clinical field strength to study in vivo sodium signal in mild traumatic brain injury
The overall goal of this project is to detect and quantify changes in brain sodium MRI (NaMRI) signal after Mild Traumatic Brain Injury (MTBI). -
Developing a Novel Neural marker for Assessing Pathological Social Interactions
We hypothesize that pathological social interactions like those observed in Autism, arise from a failure by patients to appropriately model the thoughts and plans of ... -
Assessing dysarthria severity before and after neurosurgical procedures: A prospective longitudinal study in patients with refractory movement disorders
Subjects undergoing the neurosurgical high intensity focused ultrasound (HIFU) procedure as part of their standard of care for Essential Tremor (ET) will perform three sessions ... -
Stress and Anxiety Effects on Valuation
The purpose of this study is to understand how stress, anxiety, and negative affect change learning and decision-making processes.
This study will enroll healthy volunteers ... -
Genetic Analysis of Hirschsprung Disease
Hirschsprung disease (HSCR) is a birth defect resulting from the absence of nerve (ganglion) cells in the gastrointestinal tract. Hirschsprung disease has a population incidence ... -
Phenotypic and genotypic study of Keratoconus
Keratoconus is a disease in which the cornea is abnormally steep and thin. It affects approximately 1 in 2000 individuals and usually begins in the ... -
Cochlear implants and listening effort: the interaction of cognitive and sensory constraints
Hearing impairment is the third most prevalent chronic medical condition among older adults in the United States. Untreated, hearing loss can interfere with effective communication ... -
Technical Development and Optimization for Random Matrix Theory-Based Magnetic Resonance Imaging
The objective of this study is to develop new image reconstruction methods, sequences and postprocessing methods based on random-matrix-theory noise removal, for use in up ... -
A prospective randomized-controlled study to evaluate the effect of a standardized yoga practice on chronic back pain
Background: Chronic low back pain is notoriously difficult to treat and is a primary contributor to lost work days and excessive health expenditures, and whose ...