138 "Healthy volunteers" clinical trials found.
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Post-operative Immobilization and Physical Therapy Following Volar Locked Plating for Distal Radius Fractures: Are They Necessary?
188 patients treated for distal radius fractures with open reduction internal fixation using volar locked plating will be split into two study groups: a group ...Phase N/A
Interventional
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A SINGLE CENTER PILOT STUDY ESTABLISHING TEST-RETEST RELIABILITY OF SWALLOWING PRESSURES COLLECTED WITH HIGH RESOLUTION PHARYNGEAL MANOMETRY (HRPM)
Difficulty swallowing (known as dysphagia) can have devastating consequences for health and quality of life. The current gold-standard assessment tool, videofluoroscopy (VF), allows real time ...Phase N/A
Non-Interventional
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Novel Coding Strategies for Children with Cochlear Implants
Prior to the onset of deafness, the auditory brain of post-lingually deafened adults develops in response to a rich complement of spectral, temporal, and intensity ...Phase N/A Interventional
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Phenotypic and genotypic study of Keratoconus
Keratoconus is a disease in which the cornea is abnormally steep and thin. It affects approximately 1 in 2000 individuals and usually begins in the ...Phase N/A Non-Interventional
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Site for WUH TrialNet: NATURAL HISTORY STUDY OF THE DEVELOPMENT OF TYPE 1 DIABETES
Site for The TrialNet Natural History Study of the Development of T1D is divided into Screening and Monitoring stages. Each stage will require separate informed ...Phase N/A Non-Interventional
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A single-center longitudinal study of the diagnosis clinical course risk factors causes and treatment of cognitive impairment in aging Alzheimer s disease (AD) and related disorders
The purpose is to study the diagnosis, clinical course, risk factors, causes and treatment of cognitive impairment in aging, Alzheimer’s disease (AD) and related ...Phase N/A Non-Interventional
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Edwards PASCAL TrAnScatheter Valve RePair System Pivotal Clinical Trial (CLASP IID/IIF): A prospective multicenter randomized controlled pivotal trial to evaluate the safety and effectiveness of transcatheter mitral valve repair with the Edwards PASCAL Transcatheter Valve Repair System compared to Abbott MitraClip in patients with mitral regurgitation
This is a prospective, multicenter, randomized, parallel-group study to compare the safety and effectiveness of the PASCAL System to the MitraClip System for reduction of ...Phase N/A Interventional
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Investigating auditory processing in the users of auditory brainstem and cochlear implants
This is a basic investigational research study conducted with hearing impaired adults and children who use cochlear implant or auditory brainstem implant (ABI) devices. The ...Phase N/A Non-Interventional
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A Prospective Randomized Controlled Trial to Assess the Management of Moderate Aortic Stenosis by Clinical Surveillance or Transcatheter Aortic Valve Replacement : The PROGRESS Trial
This is a randomized 1:1 trial in which subjects will receive transcatheter aortic valve replacement (TAVR) with the SAPIEN 3/SAPIEN 3 Ultra transcatheter ...Phase N/A Interventional
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Dentatorubral-Pallidoluysian Atrophy Natural History and Biomarkers Study (DRPLA NHBS)
This is a prospective, limited collection of retrospective information, longitudinal, multi-national, multi-center study, observational, confirmed DRPLA-mutation carrier and a volunteer control group.Phase N/A Non-Interventional
