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IRON DEFICITS AND THEIR RELATIONSHIP WITH SYMPTOMS AND COGNITION IN PSYCHOTIC SPECTRUM DISORDERS
Psychotic Spectrum Disorders (PSD) are severe mental syndromes associated with significant lifelong impairment and high prevalence. In this proposal we aim to employ non-invasive imaging ...Phase N/A
Non-Interventional
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Unpacking the Importance of the Structural Injuries of MTBI
To find imaging biomarkers of injury associated with symptoms in patients with MTBI by discovering the relationship between structural alterations and clinical status including cognition.Phase N/A Non-Interventional
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Relationship between the ocular microbiome and pseudoexfoliation syndrome/glaucoma and cataracts
Observational study to determine the microbiome structure of the eye, mouth, and skin of subjects with pseudo exfoliation syndrome, pseudoexfoliation glaucoma, and cataracts before and ...Phase N/A Non-Interventional
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In Vivo Insights of Small Vessel Changes with Age Using Ultra-Small-Superparamagnetic-Iron-Oxide (USPIO)-Enhanced MRI
This proposal seeks to perform an observational study for developing a new imaging tool using an ultra-small-superparamagnetic-iron-oxide (USPIO) contrast agent to characterize age-related microvascular changes ...Phase N/A Non-Interventional
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Data-Driven Learning Framework for Fast Quantitative Knee Joint Mapping
We propose a rapid and robust approach for the quantitative multi-compartment assessment of knee cartilage using magnetic resonance imaging without using either exogenous contrast agent ...Phase N/A Non-Interventional
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Association between surrogates of arterial stiffness and urinary EDC in adolescents and young adults with Type 1 and Type 2 diabetes compared to age matched healthy adolescents.
Association between surrogates of arterial stiffness and urinary EDC in adolescents and young adults with Type 1 and Type 2 diabetes compared to age matched ...Phase N/A Non-Interventional
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Platelet and Endothelial Dysfunction in Psoriasis
Background: Psoriasis is a common chronic inflammatory skin disease associated with an ~50% increased risk of cardiovascular disease (CVD) compared to matched controls. The influence ...Phase N/A Non-Interventional
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Understanding CSF Clearance in Aging and Alzheimer s Brain Through Dynamic Sodium MRI
This study aim to determine: 1) how age affects CSF production, bulk flow, and drainage in the normal brain; 2) the impact of sleep on ...Phase N/A Non-Interventional
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Chronic Pain and Postoperative Cognitive Function in the Elderly: a Prospective Observational Study
To assess the possible interrelation between pre-operative chronic pain and postoperative cognitive dysfunction (POCD) in the elderly, we plan to enroll patients undergoing planned surgery ...Phase N/A Non-Interventional
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Understanding the Lived Experience of Couples Across the Trajectory of Dementia
This multi-site, observational study will focus on the experience of older couples and the impact of Alzheimer's disease or a related dementia on health ...Phase N/A Non-Interventional
