134 "Healthy volunteers" clinical trials found.
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A computational approach to optimal deactivation of cochlear implant electrodes
The goal of the present study is to use computationally driven models of speech understanding in CI users to guide the search for which combination ...Phase N/A
Interventional
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QUANTIFICATION OF MULTI-COMPARTMENT T1 RELAXATION AND MAGNETIZATION TRANSFER IN BIOLOGICAL TISSUE: FROM BIOPHYSICS TO BIOMARKERS FOR MULTIPLE SCLEROSIS
To evaluate the efficacy of multi-compartment T1 relaxation and magnetization transfer for detecting subtle changes in normal-appearing brain tissue in multiple sclerosis to detect disease ...Phase N/A
Non-Interventional
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THE ROLE OF THE MICROBIOME IN MONOZYGOTIC TWINS WITH PSORIASIS AND PSORIATIC ARTHRITIS
We propose a longitudinal study of monozygotic twins discordant for psoriatic disease. Subjects will be characterized with detailed clinical questionnaires in addition to blood, fecal ...Phase N/A Non-Interventional
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Mechanisms of Vascular Aneurysms
Our mission is to enable the use of human tissues with outcome data by basic and clinical investigators for research into the biology, causes, prevention ...Phase N/A Non-Interventional
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The Role of Residual Hearing in Cochlear Implant Outcomes
Cochlear implants (CIs) have the potential to restore high frequency hearing electrically while maintaining residual low frequency hearing, allowing for simultaneous electric and acoustic listening ...Phase N/A Non-Interventional
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Genetic Analysis of Hirschsprung Disease
Hirschsprung disease (HSCR) is a birth defect resulting from the absence of nerve (ganglion) cells in the gastrointestinal tract. Hirschsprung disease has a population incidence ...Phase N/A Non-Interventional
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ADAPTATION TO FREQUENCY-PLACE FUNCTIONS IN COCHLEAR IMPLANT USERS
It is a basic study that will examine adaptation to frequency-place maps in cochlear implant users. The main outcome measures will be measures of speech ...Phase N/A Non-Interventional
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Locus-coeruleus function in normal elderly and AD risk (LEAD)
Growing evidence suggests that Alzheimer’s disease (AD) pathological changes begin decades before clinical symptoms and tau abnormalities in the locus coeruleus (LC) can be ...Phase N/A Interventional
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A prospective randomized-controlled study to evaluate the effect of a standardized yoga practice on chronic back pain
Background: Chronic low back pain is notoriously difficult to treat and is a primary contributor to lost work days and excessive health expenditures, and whose ...Phase N/A Interventional
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A Randomized Comparative Effectiveness Study of Staged Complete Revascularization with Percutaneous Coronary Intervention to Treat Coronary Artery Disease vs Medical Management Alone in Patients with Symptomatic Aortic Valve Stenosis undergoing Elective Transfemoral Transcatheter Aortic Valve Replacement: The COMPLETE TAVR Study
This study is being conducted in Aortic Stenosis patients who have undergone successful TAVR with a balloon expandable heart valve who also have coronary artery ...Phase N/A Interventional
