143 "Healthy volunteers" clinical trials found.
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Dentatorubral-Pallidoluysian Atrophy Natural History and Biomarkers Study (DRPLA NHBS)
This is a prospective, limited collection of retrospective information, longitudinal, multi-national, multi-center study, observational, confirmed DRPLA-mutation carrier and a volunteer control group.Phase N/A
Non-Interventional
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A computational approach to optimal deactivation of cochlear implant electrodes
The goal of the present study is to use computationally driven models of speech understanding in CI users to guide the search for which combination ...Phase N/A
Interventional
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QUANTIFICATION OF MULTI-COMPARTMENT T1 RELAXATION AND MAGNETIZATION TRANSFER IN BIOLOGICAL TISSUE: FROM BIOPHYSICS TO BIOMARKERS FOR MULTIPLE SCLEROSIS
To evaluate the efficacy of multi-compartment T1 relaxation and magnetization transfer for detecting subtle changes in normal-appearing brain tissue in multiple sclerosis to detect disease ...Phase N/A Non-Interventional
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THE ROLE OF THE MICROBIOME IN MONOZYGOTIC TWINS WITH PSORIASIS AND PSORIATIC ARTHRITIS
We propose a longitudinal study of monozygotic twins discordant for psoriatic disease. Subjects will be characterized with detailed clinical questionnaires in addition to blood, fecal ...Phase N/A Non-Interventional
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Mechanisms of Vascular Aneurysms
Our mission is to enable the use of human tissues with outcome data by basic and clinical investigators for research into the biology, causes, prevention ...Phase N/A Non-Interventional
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The Role of Residual Hearing in Cochlear Implant Outcomes
Cochlear implants (CIs) have the potential to restore high frequency hearing electrically while maintaining residual low frequency hearing, allowing for simultaneous electric and acoustic listening ...Phase N/A Non-Interventional
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Assessment of glutamate neurotransmission brain bioenergetics and neuroinflammation in major depressive disorder using TSPO PET and MRI
The overarching goal of this study is to develop PET/MR techniques for the diagnosis of Major Depressive Disorder (MDD). Our central hypothesis is that ...Phase N/A Non-Interventional
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Genetic Analysis of Hirschsprung Disease
Hirschsprung disease (HSCR) is a birth defect resulting from the absence of nerve (ganglion) cells in the gastrointestinal tract. Hirschsprung disease has a population incidence ...Phase N/A Non-Interventional
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Heart Attack Research Program (HARP)
The Heart Attack Research Program (HARP) is a multi-discipline and mutli-center study that incorporates clinical and basic science and population health to investigate mechanisms of ...Phase N/A Non-Interventional
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ADAPTATION TO FREQUENCY-PLACE FUNCTIONS IN COCHLEAR IMPLANT USERS
It is a basic study that will examine adaptation to frequency-place maps in cochlear implant users. The main outcome measures will be measures of speech ...Phase N/A Non-Interventional
