11 "Multiple sclerosis" clinical trials found.
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A Wearable Remote Data Capture Solution for Home-Based Gait Assessment in Multiple Sclerosis
The purpose of this study is to validate a quantitative way to assess mobility (e.g., gait) at-home in patients with multiple sclerosis (MS). The ... -
Transcranial Direct Current Stimulation (tDCS) for the Management of Multiple Sclerosis Related Fatigue
The purpose of this study is to determine if tDCS (short for transcranial direct current stimulation) can be used to manage the MS symptoms of ... -
Intra-Individual Variability in Cognitive Performance as a Marker of Prodromal Disability in MS
The purpose of this research study is to develop a way of detecting the very early signs of cognitive decline in patients with Multiple Sclerosis ... -
A pragmatic trial to evaluate the intermediate-term effects of early aggressive versus escalation therapy in people with multiple sclerosis
The purpose of this research is to identify the most appropriate treatment strategy for people with multiple sclerosis (MS), especially shortly after diagnosis when it ... -
Quantification of Multi-Compartment T1 Relaxation and Magnetization Transfer in Biological Tissue: From Biophysics to Biomarkers for Multiple Sclerosis
The purpose of this study is to evaluate the efficacy of multi-compartment T1 relaxation and magnetization transfer for detecting subtle changes in normal-appearing brain tissue ... -
Mesoscopic Biomarkers of Neurodegeneration and Inflammation with Diffusion MRI
The purpose of this study is to track both neurodegeneration and inflammation in multiple sclerosis (MS) disease progression by taking pictures using Magnetic Resonance Imaging ... -
Computer-Based Cognitive Assessment and Web-Based Work Status Monitoring in Relapsing Multiple Sclerosis Patients Treated with Ozanimod
The purpose of this research is to develop a registry of MS patients treated with Ozanimod that will track and relate measures of cognitive processing ... -
Health Evaluation Allostatic Load Multiple Sclerosis (HEAL-MS)
The role of childhood adversity has yet to be examined in pediatric-onset MS, despite data demonstrating that childhood adversity has been linked to earlier age ... -
A Phase 1b Study of Nivolumab in Patients with Autoimmune Disorders and Advanced Malignancies (AIM-NIVO)
We want to know the safety and tolerability of the anti-programmed death 1 (PD-1) antibody nivolumab at different dose levels for patients with autoimmune disorders ... -
A Trial of Simultaneous Transcranial Direct Current Stimulation (TDCS) and Neuroimaging
Participants (N=60) (20 Healthy Controls and 40 non-healthy participants, ie. multiple sclerosis) will be recruited to complete self-report measures and a brief cognitive assessment ...