51 "Tissue" clinical trials found.
-
WUH: Characterization of microsomal triglyceride transfer protein (MTP) in metabolic and gastrointestinal tissue in obese and other subjects undergoing therapeutic surgeries.
Microsomal triglyceride transfer protein (MTP) is an enzyme that is responsible for fat and cholesterol metabolism. Blocking the effect of MTP may be helpful in ... -
Tissue Acquisition of Arterial Aneurysms
The purpose of the study is to study the mechanisms of the natural history of aneurysms and potential circulating biomarkers in your blood. An aneurysm ... -
International CDKL5 Clinical Research Network
This study is designed for the researchers to learn more about CDKL5 deficiency disorder and how to best measure outcomes in those affected by it. -
A Phase 1 Dose-escalation and Expansion Study of the PD-1 x ILT4 Bispecific Antibody CDX-585 in Patients with Advanced Malignancies
This is a study to test a new medicine called CDX-585 on patients with advanced or spreading solid tumors that have not improved with current ...
-
A Phase 1 Open-Label Multi-Center Safety and Efficacy Study of PRT3789 in Participants with Select Advanced or Metastatic Solid Tumors with a SMARCA4 Mutation
This is a study to test a new drug called PRT3789 for safety and effectiveness in treating certain types of advanced or metastatic solid tumors ...
-
A phase 1/1b/2 study evaluating the safety tolerability pharmacokinetics pharmacodynamics and efficacy of AMG 193 alone and in combination with docetaxel in subjects with advanced MTAP-null solid tumors
This study is for adults who have advanced solid tumors that lack a certain enzyme called methylthioadenosine phosphorylase (MTAP). This study is split into two ...
-
A Modular Open-label Phase I/II Study to Evaluate the Safety Tolerability Pharmacokinetics and Efficacy of EP0031 in Patients with Advanced RET-altered Malignancies
RET alterations mostly happen in lung cancer and thyroid cancer, these alterations can be picked up on molecular testing and can be a target for ...
-
A PHASE Ib/II OPEN-LABEL MULTICENTER STUDY EVALUATING THE SAFETY ACTIVITY AND PHARMACOKINETICS OF GDC-6036 IN COMBINATION WITH OTHER ANTI-CANCER THERAPIES IN PATIENTS WITH PREVIOUSLY UNTREATED ADVANCED OR METASTATIC NON?SMALL CELL LUNG CANCER WITH A K
This study is for people with advanced or metastatic non-small cell lung cancer (NSCLC) containing a specific KRAS G12C mutation. The study is testing a ...
-
PRostate Cancer Treatment with the AQUABEAM Robotic System
This study is testing a special machine called the AQUABEAM Robotic System. This machine is designed to treat cancer tissue in the prostate. It does ...
-
The Effect of Semaglutide in Non-Cirrhotic Non-Alcoholic Steatohepatitis
We are doing this study to see if the medicine called semaglutide can help patients with NASH get better and reduce their risk of future ...