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Randomized Phase II And Phase III Studies Of Individualized Treatment For Nasopharyngeal Carcinoma Based On Biomarker Epstein Barr Virus (EBV) Deoxyribonucleic Acid (DNA)
There are two study questions we are asking in this randomized phase II/III trial based on a blood biomarker, Epstein Barr virus (EBV) deoxyribonucleic ...
Phase
Interventional
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A RANDOMIZED PHASE II/III STUDY OF PEGYLATED LIPOSOMAL DOXORUBICIN AND CTEP-SUPPLIED ATEZOLIZUMAB (IND #134427) VERSUS PEGYLATED LIPOSOMAL DOXORUBICIN/BEVACIZUMAB AND CTEP-SUPPLIED ATEZOLIZUMAB VERSUS PEGYLATED LIPOSOMAL DOXORUBICIN/BEVACIZUMAB IN PLATINUM RESISTANT OVARIAN CANCER
The purpose of this study is to compare any good and bad effects of adding Atezolizumab to the usual chemotherapy (liposomal doxorubicin) and to the ...Phase
Interventional
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i-Matter: Investigating an mHealth texting tool for embedding patient-reported data into diabetes management
This study has two phases that will be completed over the course of 5 years. Phase 1 consists of the following: (1) focus groups to ...Phase
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A Prospective Randomized Multicenter Controlled Trial of CERAMENT G as Part of Surgical Repair of Open Diaphyseal Tibial Fractures
The purpose of this study is to see if a resorbable bone filler with antibiotic, called CERAMENT|G, is safe and works well to promote ...Phase
Interventional
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ECO-RESET: A Phase 2B Randomized Double-Blind Placebo-Controlled Multiple Dose Multicenter Study to Assess Efficacy and Safety of SER-287 in Adults with Active Mild-to-Moderate Ulcerative Colitis
The purpose of this research is to study SER-287 an investigational drug, developed as a potential treatment for Ulcerative Colitis (UC). The study will look ...Phase
Interventional
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(Medley)-A Phase 2/3 Randomized Double-blind Palivizumab-controlled Study to Evaluate the Safety of MEDI8897 a Monoclonal Antibody With an Extended Half-life Against Respiratory Syncytial Virus in High-risk Children (MEDLEY)
In this study, MEDI8897 is being compared to Synagis® to determine if the effectiveness and safety of MEDI8897 is similar to Synagis®.MEDI8897 is a ...Phase
Interventional
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A Randomized Phase 2/3 Multi-Center Study of SM-88 in Subjects with Pancreatic Cancer Whose Disease Has Progressed or Recurred
This research study is conducted in two parts. Part 1 of the study is now complete. If you choose to participate in this study, you ...Phase
Interventional
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NRG-HN004 Randomized Phase II/III Trial of Radiotherapy with Concurrent MEDI4736 (Durvalumab) vs. Radiotherapy with Concurrent Cetuximab in Patients with Locoregionally Advanced Head and Neck Cancer with a Contraindication to Cisplatin.
The purpose of this study is to compare any good and bad effects of usual radiation plus the study treatment, MEDI4736 (durvalumab), to the usual ...Phase
Interventional
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BARCONA Trial: A Randomized Trial of Bardoxolone Methyl in Patients Infected with SARS-Corona Virus-2 (COVID-19)
The purpose of this research study is to find out if bardoxolone methyl is safe to use for people with COVID-19 and if it will ...Phase
Interventional
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The use of cannabidiol (CBD) in pain reduction and opioid use after shoulder arthroscopy: A Double-Blind Randomized Control Study
The purpose of this study is to see if cannabidiol (CBD) orally dissolving tablets (ODTs) following shoulder arthroscopic surgery can lessen post- surgical pain and ...Phase
