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Randomized Phase II And Phase III Studies Of Individualized Treatment For Nasopharyngeal Carcinoma Based On Biomarker Epstein Barr Virus (EBV) Deoxyribonucleic Acid (DNA)
There are two study questions we are asking in this randomized phase II/III trial based on a blood biomarker, Epstein Barr virus (EBV) deoxyribonucleic ...
Phase
Interventional
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i-Matter: Investigating an mHealth texting tool for embedding patient-reported data into diabetes management
This study has two phases that will be completed over the course of 5 years. Phase 1 consists of the following: (1) focus groups to ...Phase
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(Medley)-A Phase 2/3 Randomized Double-blind Palivizumab-controlled Study to Evaluate the Safety of MEDI8897 a Monoclonal Antibody With an Extended Half-life Against Respiratory Syncytial Virus in High-risk Children (MEDLEY)
In this study, MEDI8897 is being compared to Synagis® to determine if the effectiveness and safety of MEDI8897 is similar to Synagis®.MEDI8897 is a ...Phase
Interventional
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The use of cannabidiol (CBD) in pain reduction and opioid use after shoulder arthroscopy: A Double-Blind Randomized Control Study
The purpose of this study is to see if cannabidiol (CBD) orally dissolving tablets (ODTs) following shoulder arthroscopic surgery can lessen post- surgical pain and ...Phase
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A Seamless Adaptive Phase 2b/3 Double-Blind Randomized Placebo-controlled Multicenter International Study Evaluating the Efficacy and Safety of Belapectin (GR-MD-02) for the Prevention of Esophageal Varices in NASH Cirrhosis
The purpose of this study is to find out about the safety and efficacy (how well a drug works) of Belapectin (GR-MD-002) for the prevention ...Phase
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A Phase 2B Double-Blind Randomized Placebo-Controlled Multicenter Dose-Ranging Study to Evaluate the Efficacy and Safety Profile of PF-06700841 in Participants with Active Systemic Lupus Erythematosus (SLE)
The purpose of this study is to compare the effects of the study drug PF 06700841 tablets, at different doses with a placebo to find ...Phase
Interventional
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A Phase 3 Randomized Double-blind Placebo- and Active-controlled Parallel-group Multicenter Protocol to Evaluate the Safety and Efficacy of Guselkumab Induction and Maintenance Therapy in Subjects with Moderately to Severely Active Crohn's Disease
Under this protocol, there are 3 separate studies: a 48-week Phase 2 dose-ranging study (ie, GALAXI 1) and 2 identical 48-week Phase 3 confirmatory studies ...Phase
Interventional
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AHEP1531: Pediatric Hepatic Malignancy International Therapeutic Trial (PHITT)
This trial is the first international cooperative liver tumors trial in which a consensus approach was established by investigators representing Children’s Oncology Group (COG ...Phase
Interventional
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Site for Randomized Phase II/III Trial of Surgery and Postoperative Radiation Delivered with Concurrent Cisplatin Versus Docetaxel Versus Docetaxel and Cetuximab for High-Risk Squamous Cell Cancer of the Head and Neck
The purpose of the study is to determine whether docetaxel alone is as active as docetaxel and cetuximab combination and whether either taxane-based regimen is ...Phase
Interventional
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Metformin in Alzheimer's Dementia Prevention (MAP)
The purpose of this study is to test whether the drug Glucophage® XR (generic name metformin extended-release tablets) can prevent cognitive decline among persons with ...Phase
Interventional
