Displaying 574 (all) recruiting clinical trials.
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A PHASE II TRIAL EVALUATING THE SAFETY AND EFFICACY OF MR-LINAC- GUIDED RADIOTHERAPY AS SALVAGE TREATMENT AFTER EXTERNAL BEAM RADIOTHERAPY RECURRENCE (TUMORNATOR II)
This Phase 2 study is testing how using a special imaging technique called the Elekta Unity MR-linac system can be safe and effective for patients ...
Phase
Interventional
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TRANSCRANIAL PHOTOBIOMODULATION (tPBM) IN OLDER ADULTS WITH TRAUMATIC BRAIN INJURY: EFFECTS ON CEREBRAL BLOOD FLOW AND COGNITION
The purpose of this research study is to determine if application of near infrared energy to the forehead can change blood flow in the brains ...Phase N/A Interventional
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Evaluation of the Patellar Lift System for Subjects with Patellofemoral Cartilage Degeneration (PELICAN)
The purpose of this research study is to learn more about the Patellar LIFT System, a new device designed to relieve knee pain and improve ...Phase N/A Interventional
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A multi-center randomized (1:1) controlled phase 2 trial of STIMULAN VG with debridement and a course of systemic antibiotics vs standard of care (SoC) for the treatment of osteomyelitis associated with stage IV pressure ulcers.
This study is being performed to find out if the use of a new investigational product (meaning not approved by the Food and Drug Administration ...Phase
Interventional
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A Prospective Study to Evaluate the Safety and Efficacy of the 10 GE Xenokidney in Patients with End-stage Renal Disease (ESRD)
Each year, only about 27,000 kidney transplants are performed in the United States, leaving over 90,000 people with end stage renal disease (ESRD ...Phase
Interventional
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Monitoring of peripheral arterial disease in the lower extremities before during and after surgical intervention with dynamic vascular optical spectroscopy
The purpose of this study is to demonstrate the use of dynamic vascular optical spectroscopy (DVOS) for continuous monitoring during surgical intervention and the use ...Phase N/A
Non-Interventional
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A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated with Interstitial Lung Disease (PH-ILD)
The purpose of this patient registry is to observe, characterize, and capture real-world data from patients with Group 3 pulmonary hypertension associated with interstitial lung ...Phase
Non-Interventional
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A Phase 1a/b Study Investigating the Safety Tolerability Pharmacokinetics Pharmacodynamics and Preliminary Antitumor Activity of BGB-58067 an MTA-Cooperative PRMT5 Inhibitor in Patients With Advanced Solid Tumors
This is an open-label, multicenter, first-in-human dose escalation and dose expansion study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary antitumor activity of BGB-58067 ...Phase
Interventional
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Expanded Access Program (EAP) for Obecabtagene-Autoleucel (Obe-Cel) Out-Of-Specification (OOS) in Adult Patients with Acute Lymphoblastic Leukemia - AUTO1-OS1
The purpose of this program is to provide access to obe-cel treatment for adult patients with ALL who have undergone leukapheresis and had obe-cel manufactured ...Phase N/A Interventional
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A Phase 1/2 open label first-in-human dose escalation and expansion study for the evaluation of safety pharmacokinetics pharmacodynamics and anti-tumor activity of SAR445877 administered as monotherapy or in combination with other anticancer therapies in adults with advanced solid tumors
This is an open-label, multi-center study testing whether the study medicine, SAR445877, (new fusion protein combining anti-programmed cell death 1 (PD1) antibody with modified interleukin ...
Phase
Interventional
