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Paroxysmal nocturnal hemoglobinuria (PNH) Registry
This is a non interventional registry to gather information on the clinical presentation and outcomes of patients with PNH. The PHN Registry will capture post-marketing ...Phase
Non-Interventional
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Evaluation of Transcatheter Aortic Valve Replacement Compared to SurveilLance for Patients with AsYmptomatic Severe Aortic Stenosis: EARLY TAVR trial
The purpose of this study is to determine whether aortic valve replacement is helpful for patients who have severe, calcific, aortic stenosis (a narrowing of ...Phase
Interventional
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ClotTriever/CLOUT Registry Study
The purpose of the study is to collect information about how the ClotTriever Thrombectomy System (referred to as “ClotTriever”) works when treating deep vein thrombosis ...Phase
Interventional
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Leveraging Biomarkers for Personalized Treatment of Alcohol Use Disorder Comorbid With PTSD
The purpose of this research study is to see the short-term and long-term effects of topiramate on alcohol dependence comorbid (co-occurring) with post-traumatic stress disorder ...Phase
Interventional
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Open Label Single Arm Pilot Study to Assess Feasibility and Safety of Iron Repletion with Feraheme in Iron Deficient Patients with durable Ventricular Assist Device support
The purpose of this study is to test the feasibility of an intravenous (IV, given through a vein) medicine (Ferumoxytol) to replace iron in patients ...Phase
Interventional
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Study of the Duration and Efficacy of MYDAYIS on Adult ADHD Symptoms and Executive Function In Early Evening
The purpose of this study is to examine how well a drug called MYDAYIS works on symptoms of attention deficit/hyperactivity disorder (ADHD) and executive ...Phase
Interventional
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Prospective Multi-center Study to Evaluate the Safety and Effectiveness of the OR3O Dual Mobility System in Primary and Revision Total Hip Arthroplasty (THA) Procedures
The purpose of this study is to assess the safety and effectiveness of the OR3O™ Dual Mobility System in primary (the first time your hip ...Phase
Interventional
Accepts Healthy Volunteer
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A Prospective multicenter study to examine the influence of repairing the sub-scapularis on outcomes after reverse arthroplasty: A randomized controlled trial.
The purpose of this study is to compare the effects of repairing the subscapularis tendon to not repairing the subscapularis tendon when the AtliVate Reverse ...Phase
Interventional
Accepts Healthy Volunteer
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The Effect of Tranexamic Acid on Calculated Total Blood Loss in Anticoagulated patients undergoing Total Shoulder Arthroplasty
The purpose of this research study is to compare how well Tranexamic Acid (TXA) reduces total blood loss, surgical drain output (fluids released at the ...Phase
Interventional
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A Post-Market Clinical Evaluation of the Treatment of Femur Fractures with the Femoral Nail Piriformis Fossa (PF) of the T2 Alpha Femur Antegrade GT/PF Nailing System
The purpose of this study is to show the safety and performance of the T2 Alpha Femur Antegrade Piriformis Fossa (PF) Nail. Participants who will ...Phase
Interventional
Accepts Healthy Volunteer
