Displaying 469 (all) recruiting clinical trials.
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WUH: Characterization of microsomal triglyceride transfer protein (MTP) in metabolic and gastrointestinal tissue in obese and other subjects undergoing therapeutic surgeries.
Microsomal triglyceride transfer protein (MTP) is an enzyme that is responsible for fat and cholesterol metabolism. Blocking the effect of MTP may be helpful in ... -
A Phase 3 Study of I-Metaiodobenzylguanidine or Crizotinib Added to Intensive Therapy for Children with Newly Diagnosed High-Risk Neuroblastoma (NBL) (IND# 134379)
?The primary purpose of the study is to assess the effectiveness and safety of targeted radiopharmaceutical therapy with 131I-MIBG or crizotinib for patients with high-risk ... -
Phase 3 Accelerated BEP Trial: A randomised phase 3 trial of accelerated versus standard BEP chemotherapy for patients with intermediate and poor-risk metastatic germ cell tumours
The primary purpose of the study is to determine if accelerated BEP ((Bleomycin, Etoposide, and cisPlatin) is effective and tolerable for patients with advanced germ ... -
Study of inherited monogenic disorders in patient and tissue-specific cells
The purpose of this study is to learn more about the genetic mutations (changes) associated with the genes associated with neurodevelopmental disorders like epilepsy. Genes ... -
ACNS1833: A Phase 3 Randomized Non-Inferiority Study of Carboplatin and Vincristine versus Selumetinib (NSC# 748727 IND# 77782) in Newly Diagnosed or Previously Untreated Low-Grade Glioma (LGG) not associated with BRAFV600E Mutations or Systemic Neurofibromatosis Type 1 (NF1)
ACNS1833 is a prospective randomized phase 3 study comparing selumetinib to CV in previously untreated LGG not associated with neurofibromatosis or BRAFV600E. This non-inferiority study ... -
Quality of Life of Patients with Single-Sided Deafness Treated with Cochlear Implantation
The purpose of this research study is to understand more about how cochlear implants affect the quality of life of patients with deafness in only ... -
Single-Center Pilot Study of Living Donor Kidney Transplant from HIV-positive Donor to HIV-positive Recipient
This study will evaluate the feasibility and safety of living donor kidney transplant from an HIV-infected donor to an HIV-infected recipient. -
Human Epilepsy Project 3: Newly Diagnosed Idiopathic Generalized Epilepsy
The purpose of this research study is to identify factors that can predict how patients with idiopathic generalized epilepsy will do on a given seizure ... -
A single-center observational study of the natural history and pathogenesis of hidradenitis suppurativa
The purpose of this study is to understand the natural history and progression of Hidradenitis Suppurativa (HS) and other related disorders, and to help us ... -
Biomarkers for preterm births using non-invasive samples
The purpose of this study is to evaluate if biomarkers measured in body fluids (such as saliva, urine, vaginal fluid, and blood) in pregnant women ...