Displaying 162 (all) recruiting clinical trials.
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A Phase 1 Randomized Double-blind Placebo-controlled Single Ascending Dose Study to Evaluate the Safety Tolerability Pharmacokinetics and Pharmacodynamics of AMG 890 in Subjects With Elevated Plasma Lipoprotein(a
This research study is being conducted to learn more about the effects of a new therapy, AMG 890. In animals, AMG 890 lowered the levels ...Phase
Interventional
Accepts Healthy Volunteer
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Parent Understanding of Discharge Instructions
The purpose of the study is to find out the best way to help parents understand instructions they get from doctors and nurses on how ...Phase N/A
Non-Interventional
Accepts Healthy Volunteer
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A Phase 2 multicenter randomized double-blind placebo-controlled study to assess the efficacy safety and tolerability of AVP-786 (deudextromethorphan hydrobromide [d6-DM]/quinidine sulfate [Q]) for the treatment of neurobehavioral disinhibition including aggression agitation and irritability in patients with traumatic brain injury (TBI)
Symptoms associated with TBI such as physical and verbal aggression, agitation and irritability are problematic, can be difficult to manage, can be disruptive, and can ...Phase
Interventional
Accepts Healthy Volunteer
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Cochlear implants and listening effort: the interaction of cognitive and sensory constraints
Hearing impairment is the third most prevalent chronic medical condition among older adults in the United States. Untreated, hearing loss can interfere with effective communication ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
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Evaluation of the gut microbiome in response to treatment and clinical course of inflammatory bowel disease.
The purpose of this study is to understand how gut bacteria, the immune system, and genes differ in people with inflammatory bowel disease (IBD), specifically ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
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Functional muscle kinematics in dermatomyositis with diffusion MRI
The purpose of this study is to determine if a combination of advanced MRI techniques can be helpful in the prediction, early diagnosis, and prognosis ...Phase
Non-Interventional
Accepts Healthy Volunteer
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Optical Coherence Domain Reflectometry and Optical Coherence Tomography Measurements of Intraocular Structure
The purpose of the research to evaluate an ophthalmic imaging device called optical coherence tomography (OCT). This device is working like a camera acquiring images ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
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The Natural History of Partial Ligamentous Tears in the Wrist
The purpose of this study is to better understand common injuries in the wrist. Patients who fall or otherwise injure their hand or wrist can ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
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Phlebotomy of Healthy Adults for the Purpose of Evaluation and Validation of Immune Response and Microbiology Assays
The purpose of this study is to create a bank of different types of samples. Some of these samples might be used to develop and ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
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Risk factors for sudden unexplained death in epilepsy (SUDEP)
The purpose of this multi-site study is to build a research registry – the “North American SUDEP Registry (NASR)” to assess the risk factors and pathophysiologic ...Phase
Non-Interventional
Accepts Healthy Volunteer
