Displaying 647 (all) recruiting clinical trials.
-
A Randomized Double-Blind Placebo-Controlled Phase 3 Study to Evaluate the Efficacy and Safety of Fazirsiranin the Treatment of Alpha-1 Antitrypsin Deficiency-Associated Liver Disease with METAVIR Stage F2 to F4 Fibrosis
In this study, fazirsiran is being compared with a placebo for patients with alpha-1 antitrypsin deficiency-associated liver disease (AATD LD). A placebo is a liquid ... -
A Randomized Trial of Cryoprobe Versus Forceps for Transbronchial Biopsy (FROSTBITE-II)
Prospective, multi-center, randomized controlled trial in patients undergoing bronchoscopy with transbronchial biopsy for evaluation of diffuse parenchymal lung disease, lung transplant or pulmonary parenchymal lesions. -
A prospective double-blinded randomized controlled trial evaluating effectiveness of lower tourniquet pressures in hand surgery
The purpose of this research study is to see if lower tourniquet pressures are safe to use in the operating room. We also want to ... -
A Single Center Pilot Study on the Use of a Transcutaneous Auricular Vagus Nerve Stimulation Device in CKD Population
The purpose of this study is to test a possible treatment called transcutaneous auricular vagal nerve stimulation (TaVNS) in patients with chronic kidney disease (CKD ... -
Insomnia and its association with myasthenia gravis and peripheral neuropathy
The purpose of the study is to:- Better understand how sleep affects quality of life and fatigue in people with myasthenia gravis (MG).
- Better understand ...
-
A Phase 3 Multicenter Randomized Double-blind Placebo-controlled Trial to Evaluate the Efficacy and Safety of Sibeprenlimab Administered Subcutaneously in Subjects with Immunoglobulin A Nephropathy
The purpose of this study is to evaluate the safety and effectiveness of an investigational drug called Sibeprenlimab. An investigational drug is a drug that ... -
A multicenter international randomized placebo controlled double-blind parallel group and event driven Phase 3 study of the oral FXIa inhibitor asundexian (BAY 2433334) for the prevention of ischemic stroke in male and female participants aged 18 years or older.
OCEANIC-STROKE (study 20604) is a multicenter, international, randomized, placebo controlled, double-blind, parallel group, event driven phase 3 study. The purpose of this study is to ... -
A Phase 3 Randomized Double-Blind Placebo-Controlled Study to Evaluate the Efficacy and Safety of Deucravacitinib in Participants with Active Systemic Lupus Erythematosus (POTEYK-SLE-1)
Researchers hope to learn more about whether deucravacitinib can help in the treatment of SLE and how safe it is to use in people with ... -
A SINGLE-SITE OBSERVATIONAL STUDY ON THE ABILITY OF DYNAMIC VASCULAR OPTICAL SPECTROSCOPY TO MONITOR THE HEALTH OF THE CAROTID ARTERY
The purpose of this study is to validate the use of dynamic vascular optical spectroscopy (DVOS) for monitoring oxygen saturation in the carotid artery, we ... -
An Evaluation of Home Urinalysis Testing for Systemic Lupus Erythematosus (SLE) Patients at Elevated Risk for Developing Lupus Nephritis: A Pilot Stage and Randomized Controlled Study
In this pilot study participants who enrolled in the SAMPLE Biorepository (s14-00487), who have provided permission to be contacted for future research, will be invited ...