Displaying 697 (all) recruiting clinical trials.
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A PHASE 1B/2 MULTICENTER OPEN-LABEL STUDY OF IFINATAMAB DERUXTECAN (I-DXd) A B7-H3 ANTIBODY-DRUG CONJUGATE (ADC) IN COMBINATION WITH ATEZOLIZUMAB WITH OR WITHOUT CARBOPLATIN AS FIRST-LINE INDUCTION OR MAINTENANCE IN SUBJECTS WITH EXTENSIVE-STAGE SMALL CELL LUNG CANCER (ES-SCLC) (IDeate-Lung03)
This global study is designed to test how safe and effective the drug I-DXd is when combined with atezolizumab, with or without carboplatin. The treatment ...
Phase
Interventional
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An Open-label Phase 1 Multicenter Study to Evaluate the Safety and Preliminary Anti-tumor activity of NT-112 in Human Leukocyte Antigen-C*08:02-Positive Adult Subjects with Unresectable Advanced and/or Metastatic Solid Tumors That Are Positive for the KRAS G12D Mutation
This study is testing a NT-112, a type of cellular therapy, in patients with advanced cancer, such as lung, pancreatic, or colorectal cancer, who have ...
Phase
Interventional
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Site for Intermediate Patient Population Expanded Access Protocol for MBP134 for Participants with Sudan Virus Disease (SVD)
The goal of this study is to see if a drug called MBP134 works to help patients get better from Sudan Virus Disease (SVD).Phase N/A Interventional
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Randomized Double-Blind Placebo-controlled Safety Study of Glial Cell Line-Derived Neurotrophic Factor Gene Transfer (AAV2-GDNF) in Multiple System Atrophy
In this clinical trial, we are testing a drug called glial cell line-derived neurotrophic factor (GDNF) gene transfer to see if it helps people with ...Phase
Interventional
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PATH Inventprise Inc. Phase 1/2 Group B Streptococcus Investigational Vaccine Clinical Trial
The purpose of this study is to gain understanding of the safety, tolerability, and immunogenicity of a new Group B streptococcus (GBS) investigational vaccine (IVT ...Phase
Interventional
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A Multi-Center Prospective Non-Interventional Study of Real-World Effectiveness of Etrasimod in Patients with Ulcerative Colitis (ENDEAVOUR-UC)
The purpose of this research study is to observe the effectiveness of Etrasimod (Velsipity®) in adults with moderately to severely active ulcerative colitis (UC).
The ...Phase
Interventional
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A Phase 3 Randomized Open-Label Study to Compare the Efficacy and Safety of Anitocabtagene Autoleucel Versus Standard of Care Therapy in Participants With Relapsed/Refractory Multiple Myeloma
This study is testing the efficacy and potential side effects of a novel CAR-T cell treatment called anitocabtagene autoleucel (anito-cel). It is being compared to ...
Phase
Interventional
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A Prospective Observational Sub-Study of the Global Hypophosphatasia Registry to Describe the Potential Risk of Immune-Mediated Loss of Pharmacological Effect of Asfotase Alfa in Participants with Hypophosphatasia (HPP)
This study collects observational Standard of Care (SOC) data in patients currently receiving asfotase alfa or about to start treatment with asfotase alfa as determined ...Phase N/A
Non-Interventional
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Environmental influences on Child Health Outcomes (ECHO) Cohort Data and Biospecimen Collection Protocol: The NYU Children's Health and Environment Study (NYU CHES) ECHO Cohort Study Site
ECHO is a nationwide research program whose mission is to enhance the health of children for generations to come.The goal is to learn how ...Phase N/A Non-Interventional
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A Phase II Clinical Trial of Candida Therapeutic Vaccine in Head and Neck Cancer Patients to Reduce Recurrence
This study is designed to test a treatment called STK-012 for patients with advanced solid tumors. It is an open-label trial, meaning both the researchers ...
Phase
Interventional
