-
Site for AAML1831: A phase 3 randomized trial for patients with de novo AML comparing standard therapy including gemtuzumab ozogamicin GO to CPX-351 with GO and the addition of the FLT3 inhibitor gilteritinib for patients with FLT3 mutations
Site for This phase III trial compares standard chemotherapy to therapy with CPX-351 and/or gilteritinib for patients with newly diagnosed acute myeloid leukemia with ...Phase
Interventional
-
Edwards PASCAL TrAnScatheter Valve RePair System Pivotal Clinical Trial (CLASP IID/IIF): A prospective multicenter randomized controlled pivotal trial to evaluate the safety and effectiveness of transcatheter mitral valve repair with the Edwards PASCAL Transcatheter Valve Repair System compared to Abbott MitraClip in patients with mitral regurgitation
This is a prospective, multicenter, randomized, parallel-group study to compare the safety and effectiveness of the PASCAL System to the MitraClip System for reduction of ...Phase N/A Interventional
Accepts Healthy Volunteer
-
Serologic Testing and Genomic Analysis of Autoimmune Immune-Mediated and Rheumatic Patients with COVID-19 (SAGA)
This is a prospective cohort study involving all subjects enrolled in the Web-based Assessment of Autoimmune, Immune-Mediated, and Rheumatic Patients during the COVID-19 Pandemic (WARCOV ...Phase N/A
Non-Interventional
-
Technical Development and Optimization for Random Matrix Theory-Based Magnetic Resonance Imaging
The objective of this study is to develop new image reconstruction methods, sequences and postprocessing methods based on random-matrix-theory noise removal, for use in up ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
-
Impact of Weight Loss in Patients with Hypertrophic Cardiomyopathy
This is an observational imaging study to evaluate the cardiac effects of weight loss in obese patients with a BMI >=30 with a confirmed diagnosis ...Phase N/A Non-Interventional
-
Gut microbiome alterations as a mechanism of immune dysregulation in new-onset refractory status epilepticus (NORSE)
We will perform a prospective, observational cohort study, with biospecimen collection, of NORSE subjects and subjects with status epilepticus of known cause (e.g. epilepsy ...Phase N/A Non-Interventional
-
Site for A 78-week trial comparing the effect and safety of once weekly insulin icodec and once daily insulin glargine 100 units/mL both in combination with non-insulin anti-diabetic treatment in insulin na ve subjects with type 2 diabetes
Site for To demonstrate the effect on glycaemic control of once weekly insulin 287, with or without non-insulin anti-diabetic drugs, in insulin naïve subjects with ...Phase
Interventional
-
NEW YORK OSTEOARTHRITIS HAND COHORT
This is an observational, longitudinal registry of patients with hand osteoarthritis (HOA) that broadly aims to assess the clinical spectrum, risk factors, and identify possible ...Phase N/A Non-Interventional
-
Platelet and Endothelial Dysfunction in Psoriasis
Background: Psoriasis is a common chronic inflammatory skin disease associated with an ~50% increased risk of cardiovascular disease (CVD) compared to matched controls. The influence ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
-
Investigating auditory processing in the users of auditory brainstem and cochlear implants
This is a basic investigational research study conducted with hearing impaired adults and children who use cochlear implant or auditory brainstem implant (ABI) devices. The ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
