Displaying 499 (all) recruiting clinical trials.
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A Phase 2 Randomized Study of Adjuvant Immunotherapy With the Personalized Cancer Vaccine mRNA-4157 and Pembrolizumab Versus Pembrolizumab Alone After Complete Resection of High-Risk Melanoma (mRNA-4157-P201)
The purpose of this research study is to test whether the combination of the study drugs pembrolizumab and mRNA-4157 works better than just pembrolizumab to ...Phase
Interventional
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Neuropsychological consultation as part of pediatric diabetes care: Does it improve glycemic control and family functioning?
The purpose of this research study is to learn more about neuropsychological consultations (or testing designed to measure different brain functions) and diabetes care, and ...Phase N/A Interventional
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SWIFT TRIAL: SURGICAL WEIGHT-LOSS TO IMPROVE FUNCTIONAL STATUS TRAJECTORIES FOLLOWING TOTAL KNEE ARTHROPLASTY
In many patients, obesity is associated with arthritis in the knee that causes pain and difficulty moving or walking, which may get worse over time ...Phase N/A Interventional
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Zenith p-Branch Pivotal Study
The purpose of this study is to assess the safety of the Zenith® p-Branch® and how well it works in combination with Atrium iCAST™ covered ...Phase
Interventional
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A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients with Advanced Solid Tumors with KRAS G12C Mutation
The purpose of this study is to test the safety, tolerability, and effectiveness of MRTX849 (called “the study drug” from now on) for advanced cancers ...Phase
Interventional
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A phase III randomized double blind parallel group placebo controlled international multicentre study to assess efficacy and safety of Cx601 adult allogeneic expanded adipose-derived stem cells (eASC) for the treatment of complex perianal fistula(
The purpose of this study is to confirm (1) how well the investigational drug, Cx601, works at a single dose of 120 million cells compared ...Phase
Interventional
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THE PROSPECTIVE NATURAL HISTORY OF FAMILIAL DYSAUTONOMIA
To create a database of clinical information collected from you/your child’s medical chart on a yearly basis from patients with familial dysautonomia (FD ...Phase N/A
Non-Interventional
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MICROBiome Involvement in Outcomes of Methotrexate Efficacy-RA
This is a prospective, observational, proof-of-principle study looking at the effects of the gut microbiome on the metabolism and response to methotrexate treatment and related ...Phase N/A Non-Interventional
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Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking ( APS ACTION ) International Clinical Database and Repository
This is a registry study, which collects information about patients and puts it in a computer program called a database. The purpose of this study ...Phase N/A Non-Interventional
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Craniomaxillofacial Allotransplantation (Face Transplant)
The purpose of this study is to see if an investigational surgery that transfers tissue from a non-living donor to living individual will help restore ...Phase N/A Interventional
