Displaying 581 (all) recruiting clinical trials.
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MINERALOCORTICOID RECEPTOR ANTOGONISM IN ATHEROSCLEROSIS (MAGMA-ADDON)
Atherosclerotic disease, or hardening of the arteries, is characterized by the thickening of the arterial walls due to fatty deposits in wall and inflammation in ...Phase N/A
Interventional
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Transcranial Direct Current Stimulation (tDCS) for the Management of Multiple Sclerosis Related Fatigue
The purpose of this study is to determine if tDCS (short for transcranial direct current stimulation) can be used to manage the MS symptoms of ...Phase
Interventional
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The AIM-HN and SEQ-HN Study: A 2 Cohort Non-comparative Pivotal Study Evaluating the Efficacy of Tipifarnib in Patients with Head and Neck Squamous Cell Carcinoma (HNSCC) with HRAS Mutations (AIM-HN) and the Impact of HRAS Mutations on Response to First Line Systemic Therapies for HNSCC (SEQ-HN)
The purpose of this research study is to see how effective the study drug is to treat your tumor. Other reasons for conducting the study ...Phase N/A Interventional
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Zoster Eye Disease Study (ZEDS): A multi-center randomized double-masked placebo-controlled clinical trial of suppressive valacyclovir for one year in immunocompetent study participants with an episode of dendriform epithelial keratitis stromal keratitis endothelial and/or iritis due to Herpes Zoster Ophthalmicus (HZO) in the year prior to enrollment
The purpose of this study is to find out whether one year of a low dose of the medicine valacyclovir reduces complications of shingles affecting ...Phase N/A Interventional
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Combined Phase 3 Double-blind Randomized Placebo-Controlled Studies Evaluating the Efficacy and Safety of Filgotinib in the Induction and Maintenance of Remission in Subjects with Moderately to Severely Active Crohn s Disease
The purpose of this study is to see if filgotinib is effective and safe in treating people with moderate to severe Crohn’s disease. The ...Phase
Interventional
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Edwards PASCAL TrAnScatheter Mitral Valve RePair System Pivotal Clinical Trial (CLASP IID): A prospective multicenter randomized controlled pivotal trial to evaluate the safety and effectiveness of transcatheter mitral valve repair with the Edwards PASCAL Transcatheter Mitral Valve Repair System compared to Abbott MitraClip in patients with degenerative mitral regurgitation (DMR)
The goal of this study is to assess the safety and performance of the PASCAL System in patients with symptomatic degenerative mitral regurgitation (DMR) who ...Phase N/A Interventional
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Measurement of Thrombelastography as an alternative means to guide blood product use before invasive procedures in cirrhosis with severe coagulopathy: An observational study
The purpose of this study is to test the use of a blood test known as thromboelastography (TEG). This study will help us see if ...Phase N/A
Non-Interventional
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Ferric Carboxymaltose to Improve Skeletal Muscle Metabolism in Heart Failure Patients with Functional Iron Deficiency
The purpose of this study is to better understand how body levels of iron affect the ability to exercise in patients with heart failure. Heart ...Phase
Interventional
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A Phase 3 Multinational Randomized Placebo-controlled Study of ARRY-371797 in Patients with Symptomatic Dilated Cardiomyopathy Due to a Lamin A/C Gene Mutation
This multinational Phase 3 study will evaluate the efficacy, safety and PK following treatment with ARRY-371797 compared with placebo (1:1 randomization) in at least ...Phase
Interventional
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CHARM: Glibenclamide for Large Hemispheric Infarction Analyzing mRS and Mortality. A Multicenter Double-Blind Placebo-Controlled Randomized Parallel-Group Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 for Severe Cerebral Ed
This is a Phase 3 study, which means that BIIB093 (study drug) has already been investigated in previous clinical research studies with a small number ...Phase
Interventional
