Displaying 581 (all) recruiting clinical trials.
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Translating the ISCHEMIA trial into a Shared Decision-Making Tool for chronic stable CAD
The purpose of this research study is to learn more about how patients with Coronary Artery Disease(CAD) make decisions about their CAD treatment. The ... -
Transbronchial Biopsy Assisted by Robot Guidance in the Evaluation of Tumors of the Lung (TARGET trial)
The Monarch Robotic Endoscopy research study uses a platform medical device that gives your doctor the ability to control a bronchoscope using a remote control ... -
A Phase I/II Randomized Double-Blind Placebo-Controlled Trial of Cannabidiol for chronic radiculopathic pain syndromes maintained on chronic opioid therapy
The purpose of this research study is to see how safe and effective Cannabidiol (CBD) is for the treatment of chronic non-cancer spinal radiculopathic pain ... -
Single-arm open label phase II study of MBG453 (sabatolimab) added to FDA approved Hypomethylating agents of investigator s choice (IV/SC/Oral) for patients with intermediate high or very high risk myelodysplastic syndrome (MDS) as per IPSS-R criteria (US multi-center) (STIMULUS MDS-US)
The purpose of the study is to describe and evaluate safety and efficacy of MBG453 (sabatolimab) in combination with FDA approved Hypomethylating agents (HMA). We ... -
A novel Phase 2 double-blind randomized controlled clinical trial to evaluate the efficacy of centrally acting non-toxic ACE inhibition in cognitive impairment associated with SLE
This research study is being done to test the effects of centrally-acting ACE inhibitor, named lisinopril, on resting metabolism in the brain and on cognitive ... -
A Phase 2b Randomized Double-Blind Placebo-Controlled Study to Evaluate the Efficacy and Safety of MK-3655 in Individuals With Pre-cirrhotic Nonalcoholic Steatohepatitis
The purpose of this study is to see if an experimental drug called MK-3655 helps people with a liver disease called nonalcoholic steatohepatitis (NASH). “Experimental ... -
A Phase 2b Dose-Ranging Randomized Double-Blind Placebo-Controlled Multicenter Study of Rodatristat Ethyl in Patients with Pulmonary Arterial Hypertension
The purpose of this research study is to understand the effects of rodatristat ethyl in subjects with PAH. It is expected that approximately 90 subjects ... -
Interventional randomized double-blind parallel-group placebo-controlled multi-centre study to assess the efficacy safety and tolerability of Lu AF82422 in patients with Multiple System Atrophy
The purpose of this study is to find out whether a potential new treatment, the investigational drug Lu AF82422, is safe and effective in people ... -
AHCRN Registry: Characterizing Patient Populations in the Adult Hydrocephalus Clinical Research Network (AHCRN)
The purpose of this research project is to develop a patient registry, or database, for data collected during routine medical care of patients with hydrocephalus ... -
The BAMM2 (BRAF Autophagy MEK inhibition in Melanoma) Study: A Randomized Double Blind Phase II Study of Dabrafenib and Trametinib with or without Hydroxychloroquine in Advanced BRAFV600E/K Melanoma with elevated LDH
Hydroxychloroquine inhibits a process called autophagy which helps tumors survive. The purpose of the study is to see how well different treatments work when hydroxychloroquine ...