Displaying 578 (all) recruiting clinical trials.
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A multi-center randomized double-blind placebocontrolled parallel group phase III study to evaluate the efficacy and safety of LNP023 in primary IgA nephropathy patients
The purpose of the study is to find out if LNP023 (also called iptacopan) is safe and effective in people who have primary IgA Nephropathy ...Phase
Interventional
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A Study Of Nivolumab In Combination With Trametinib With Or Without Ipilimumab In Participants With Previously Treated Metastatic Colorectal Cancers
The purpose of the study is to characterize the safety and efficacy profile of a combination of anti-cancer therapies in participants with previously treated metastatic ...Phase
Interventional
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A Phase 1/2 Dose Escalation And Dose Expansion Study Of BA3021 Alone And In Combination With Nivolumab In Patients With Advanced Solid Tumors
The purpose of the study is to determine and evaluate the safety, tolerability, immunogenicity, and antitumor activity of BA3021 alone and in combination with nivolumab ...Phase
Interventional
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Goal-Directed Cardiopulmonary Resuscitation in Cardiac Arrest Using a Novel Physiological Target: A Pilot Mechanistic Randomized Control Trial
The proposed study is a single-center, randomized controlled pilot trial of adults who suffer in-hospital cardiac arrests. Using cerebral oxygenation and end-tidal carbon dioxide physiological ...Phase
Interventional
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Post COVID-19 Hypoxemic Respiratory Failure Residual Pathophysiologic Outcomes
The purpose of this study is to learn about the natural history of COVID-19 and its causes and see what effects it has on the ...Phase N/A
Non-Interventional
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A 24-week Study to Evaluate The Safety and Efficacy of CNTX-6970 in Subjects with Moderate to Severe Knee Osteoarthritis Pain
The purpose of this study is to see if a new experimental drug, called CNTX-6970, is safe and works for people with chronic pain from ...Phase
Interventional
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Interventional randomized double-blind crossover placebo controlled exploratory phase Ib study investigating the safety tolerability pharmacokinetic and electrocorticographic response of Lu AG06466 in treatment resistant focal epilepsy patients with chronically implanted responsive neurostimulation system (RNS System).
The purpose of this study is to find out about the safety and efficacy (how well something works) of Lu AG06466 for the treatment of ...Phase
Interventional
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THE NEPHROTIC SYNDROME STUDY NETWORK (NEPTUNE)
Childhood onset nephrotic syndrome is a condition which affects the kidneys causing them to leak protein from the blood into the urine. Nephrotic syndrome is ...Phase N/A Non-Interventional
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A single-center pilot study evaluating the safety and efficacy of a preemptive short course of glecaprevir/pibrentasvir in hepatitis C positive to negative kidney transplantation
The purpose of this research study is to evaluate the feasibility of a 2 week course of glecaprevir/pibrentasvir (Mavyret) starting immediately prior to transplantation ...Phase
Interventional
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Significance and Outcome of Magnetic Resonance Enterography Revealing Sacroiliitis in Crohn s Disease
This study aims to further define and characterize imaging findings of possible sacroiliitis in Crohn’s Disease patients by recalling subjects who had findings of ...Phase N/A Interventional
