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A Phase 3 Randomized Double- Or Observer-Blinded Placebo-Controlled Trial to Evaluate the Efficacy and Safety of a Respiratory Syncytial Versus (RSV) Prefusion F Subunit Vaccine in Infants Born To Women Vaccinated During Pregnancy
The purpose of this study is to find out if Pfizer’s investigational RSVpreF vaccine prevents the development of RSV illness in your baby. A ...Phase
Interventional
Accepts Healthy Volunteer
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Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly
Fetal complete (i.e., third degree) atrioventricular block (AVB), identified in the 2nd trimester of pregnancy in an otherwise normally developing heart, is almost universally ...Phase
Interventional
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The Safety and Effectiveness of DuraSorb for Lower Pole Reinforcement in Patients Undergoing 2 Stage Breast Reconstruction
The purpose of this research is to test the safety and performance of DuraSorb® mesh when used to support your expander during 2-stage breast reconstruction ...Phase N/A Interventional
Accepts Healthy Volunteer
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A Phase 2 Basket Study of Tucatinib in Combination With Trastuzumab in Subjects With Previously Treated Locally Advanced Unresectable or Metastatic Solid Tumors Driven by HER2 Alterations
The purpose of the study is to determine how well tucatinib works with trastuzumab for solid tumors that make either more HER2 or a different ...Phase
Interventional
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An Umbrella Study of INCMGA00012 Alone and in Combination With Other Therapies in Participants With Advanced or Metastatic Endometrial Cancer Who Have Progressed on or After Platinum-Based Chemotherapy (POD1UM-204)
The purpose of the study is to determine the safety and efficacy of INCMGA00012 monotherapy or in combination with other immunotherapy or targeted agents (combinations ...Phase
Interventional
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The COMPASSHER2 Trials (COMprehensive Use of Pathologic Response ASSessment to Optimize Therapy in HER2-Positive Breast Cancer): COMPASSHER2 Residual Disease (RD) A Double-Blinded Phase III Randomized Trial of T-DM1 Compared with T-DM1 and Tucatinib
The purpose of the study is to determine if the invasive disease-free survival (iDFS) with T-DM1 and tucatinib is superior to the iDFS in the ...Phase
Interventional
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A Phase 1 Open-Label Safety Pharmacokinetic and Preliminary Efficacy Study of STRO-002 an Anti-Folate Receptor Alpha (FolRa) Antibody-Drug Conjugate (ADC) in Patients With Advanced Epithelial Ovarian Cancer (Including Fallopian Tube or Primary Peritoneal Cancers) and Endometrial Cancers
The purpose of the study is to determine the safety and efficacy of STRO-002, which is a antibody drug conjugate (ADC) given intravenously every 3 ...Phase
Interventional
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Psychological Impact of Covid-19 on Postpartum Period of Parous Mothers: A Retrospective Case Series
The purpose of this research study is to assess the impact of COVID on postpartum wellbeing. This research study is being done to collect the ...Phase N/A
Non-Interventional
Accepts Healthy Volunteer
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A Pilot Study of the Immediate Effects of DLPFC tDCS on Attention Bias in Depression
The purpose of this study is to determine if a single 30-minute session of transcranial direct current stimulation, or tDCS, can help people with mild ...Phase N/A Interventional
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Reach Out Stay Strong Essentials for mothers of newborns (ROSE) Adaptation for Chinese American mothers
The study is a cultural adaptation and pilot study of a postpartum depression prevention intervention among pregnant Chinese American women. The study consists of focus ...Phase
Interventional
Accepts Healthy Volunteer
