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A Feasibility Study Examining Conscious Awareness and Mental and Cognitive Experiences During Deep Hypothermic Circulatory Arrest
Some people who have been unconscious for any reason have sometimes described having certain memories and thought processes during the event. They may have seen ... -
Cardiac Arrest Awareness and Long-Term Quality of Life: a Mixed Methods Study of the Experiences and Psychological Consequences of Adult Cardiac Arrest.
The purpose of this research study is to better understand memories or experiences during cardiac arrest, the long-term psychological effects and quality of life of ... -
Percutaneous MitraClipTM Device or Surgical Mitral Valve REpair in PAtients with PrImaRy MItral Regurgitation who are Candidates for Surgery (REPAIR-MR)
The purpose of this research study is to see how effective the MitraClip™ system is for treating patients who are candidates for Mitral Valve (MV ... -
First-in-human open-label dose-escalation trial with expansion cohorts to evaluate safety of GEN1046 in subjects with malignant solid tumors
The purpose of the study is to determine the safety of GEN1046 in patients with malignant solid tumors. GEN1046 is investigational drug in this study ... -
The Effect of Tranexamic Acid on Calculated Total Blood Loss in Anticoagulated patients undergoing Total Shoulder Arthroplasty
The purpose of this research study is to compare how well Tranexamic Acid (TXA) reduces total blood loss, surgical drain output (fluids released at the ... -
A Phase II Study of Talimogene laherparepvec Followed by Talimogene laherparepvec + Nivolumab in Refractory T Cell and NK Cell Lymphomas Cutaneous Squamous Cell Carcinoma Merkel Cell Carcinoma and Other Rare Skin Tumors
The purpose of the study is to determine the safety and efficacy of talimogene laherparepvec monotherapy followed by combination therapy with nivolumab (NIVO) for patients ... -
MULTICENTER PHASE II NEOADJUVANT AND ADJUVANT STUDY OF ALECTINIB ENTRECTINIB OR VEMURAFENIB PLUS COBIMETINIB IN PATIENTS WITH STAGES I-III NON-SMALL CELL LUNG CANCER WITH ALK ROS1 NTRK OR BRAF V600E MOLECULAR ALTERATIONS
The purpose of the trial is to determine the efficacy and safety of drugs in patients with untreated non-small cell lung cancer (NSCLC) tumors. In ... -
An Observational Longitudinal Oligo-Center Study to Define Clinical Biofluid Imaging and Digital Outcome Measures in Multiple System Atrophy
This research study is an observational, non-interventional, study to define changes in clinical, neurological, blood, spinal fluid, and neuroimaging (MRI) biomarkers (A biomarker is a ... -
COVID-19 Study for New and Expecting Moms
This is a study that will examine the impact of COVID-19 on experiences of pregnant and new mothers and the relevance of these experiences to ... -
ADVANCED DIFFUSION IMAGING IN RENAL TISSUE: TECHNICAL OPTIMIZATION
The objective of this study is to optimize imaging protocols and analysis for advanced magnetic resonance imaging (MRI) of the kidney.The study will see ...