Displaying 741 (all) recruiting clinical trials.
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Technical Development and Optimization for Random Matrix Theory-Based Magnetic Resonance Imaging
The purpose of this research study is to develop new MRI software processing techniques to eliminate excess information collected during the scan and to try ...Phase N/A
Non-Interventional
Accepts Healthy Volunteer
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A randomized treatment open-label dose-blinded parallel group three arm proof-of-concept clinical trial to investigate the efficacy and safety of LNP023 compared with rituximab in the treatment of subjects with idiopathic membranous nephropathy
The purpose of the study is to find out if the drug called “LNP023” is safe and has beneficial effects in people who have membranous ...Phase
Interventional
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A Three-Arm Study of ME-401 Monotherapy in Subjects with Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) or Follicular Lymphoma (FL) of ME-401 in Combination with Rituximab in Subjects with Relapsed/Refractory CLL/SLL or B-cell Non-Hodgkin s Lymphoma (NHL) and of ME-401 in Combination with Zanubrutinib in Subjects with Relapsed/Refractory CLL/SLL or B-cell NHL
The purpose of this study is to look at how your body tolerates ME-401, how effective ME-401 may be, and how ME-401 is taken up ...Phase
Interventional
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A Phase 3 Randomized Open-Label Three Arm Study of PF-06801591 in Combination with BCG (Induction With or Without Maintenance) Versus BCG (Induction and Maintenance) in Participants with HR BCG-Na ve NMIBC (B8011006)
The purpose of the study is to determine the safety and efficacy of PF-06801591 (an anti-PD-1 antibody) combined with Bacillus Calmette- Guerin (BCG) in patients ...Phase
Interventional
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A Multicenter Randomized Double-Blind Parallel Group Placebo-Controlled Trial to Evaluate the Effect of InHospital Initiation of Dapagliflozin on Clinical Outcomes in Patients with Heart Failure with Reduced Ejection Fraction Who Have Been Stabilized During Hospitalization for Acute Heart Failure
This study will test whether the drug dapagliflozin is safe and has beneficial effects when added to conventional heart failure therapy in patients who have ...Phase
Interventional
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A RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED PARALLEL GROUP MULTICENTER TRIAL OF CVL-865 AS ADJUNCTIVE THERAPY IN ADULTS WITH DRUG-RESISTANT FOCAL ONSET SEIZURES (REALIZE TRIAL)
The purpose of this study is to learn how well an investigational drug (referred to as “study drug”) called CVL-865 works as a possible treatment ...Phase
Interventional
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A Double-Blind Randomized Placebo-Controlled Study and Open-Label Long Term Extension of study drug in Patients with Primary Biliary Cholangitis with Inadequate Response or Intolerance to Ursodeoxycholic Acid
The main purpose is to study the effect of daily oral administration of 80 mg elafibranor on cholestasis (impairment of bile formation and/or bile ...Phase
Interventional
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Optimization and evaluation of accelerated MRI for prostate imaging
The objective of this study is to develop fast or accelerated Magnetic Resonance Imaging (MRI) methods for prostate imaging. Current prostate imaging, which is performed ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
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Phase 1/1b Study to Evaluate the Safety & PK of JNJ-73841937 a Third Generation EGFR-TKI as Monotherapy or in Combinations With JNJ-61186372 a Human Bispecific EGFR and cMet Antibody in Participants With Advanced NSCLC
The purpose of the study is to determine the safety and tolerability of JNJ-73841937 (Lazertinib), a Third Generation EGFR-TKI, as Monotherapy or in Combinations With ...Phase
Interventional
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The Effect of Tranexamic Acid on Calculated Total Blood Loss in Patients undergoing Revision Shoulder Arthroplasty
The purpose of this research study is to evaluate how well Tranexamic Acid (TXA) reduces total blood loss, surgical drain output (fluids released at the ...Phase
Interventional
