Displaying 741 (all) recruiting clinical trials.
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Clinical Relevance of Accuracy of Basal Joint Injections
The purpose of this study is to better understand the accuracy of steroid injections into the joint at the base of the thumb for patients ...Phase N/A
Non-Interventional
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Synucleinopathy and Constipation: A Prospective Observational Study of the Physiology of Constipation in Comparison to Chronic Idiopathic Constipation
The purpose of this study is to examine the mechanisms of constipation among patients with synucleinopathies such as Parkinson’s disease (PD) and multiple system ...Phase N/A Non-Interventional
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A Phase 1 Open Label Multi-Arm Multicenter Study of MK-4830 as Monotherapy and in Combination with Pembrolizumab for Participants with Advanced Solid Tumors
This is a first-in-human (FIH), dose escalation, and dose finding trial to assess the safety and tolerability of MK-4830, both as monotherapy and as combination ...Phase
Interventional
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The Safety and Effectiveness of DuraSorb for Lower Pole Reinforcement in Patients Undergoing 2 Stage Breast Reconstruction
The purpose of this research is to test the safety and performance of DuraSorb® mesh when used to support your expander during 2-stage breast reconstruction ...Phase N/A Interventional
Accepts Healthy Volunteer
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STAMP: Surgically Treated Adjuvant Merkel cell Carcinoma with Pembrolizumab a Phase III Trial (ECOG EA6174)
This phase III trial studies how well pembrolizumab works compared to standard of care observation in treating patients with stage I-III Merkel cell cancer that ...Phase
Interventional
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Impact of Weight Loss in Patients with Hypertrophic Cardiomyopathy
The purpose of this study is to evaluate whether or not the known impact of obesity on patients with Hypertrophic Cardiomyopathy(HCM) can be improved ...Phase N/A Non-Interventional
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A Randomized Study of Daratumumab Plus Lenalidomide Versus Lenalidomide Alone as Maintenance Treatment in Patients with Newly Diagnosed Multiple Myeloma Who Are Minimal Residual Disease Positive After Frontline Autologous Stem Cell Transplant
The current study is being conducted to evaluate the MRD negativity conversion rate following the addition of daratumumab to lenalidomide, when administered as maintenance treatment ...Phase
Interventional
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A Seamless Adaptive Phase 2b/3 Double-Blind Randomized Placebo-controlled Multicenter International Study Evaluating the Efficacy and Safety of Belapectin (GR-MD-02) for the Prevention of Esophageal Varices in NASH Cirrhosis
The purpose of this study is to find out about the safety and efficacy (how well a drug works) of Belapectin (GR-MD-002) for the prevention ...Phase
Interventional
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Gut microbiome alterations as a mechanism of immune dysregulation in new-onset refractory status epilepticus (NORSE)
The purpose of this study is to learn more about and compare the role of gut dysfunction in cases of new-onset refractory status epilepticus (NORSE ...Phase N/A Non-Interventional
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Post-operative Immobilization and Physical Therapy Following Volar Locked Plating for Distal Radius Fractures: Are They Necessary?
The purpose of this study is to see if splinting and formal physical therapy are necessary following surgical fixation (immobilization) of distal radius fractures (broken ...Phase N/A Interventional
Accepts Healthy Volunteer
