Displaying 735 (all) recruiting clinical trials.
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An open-label phase I multi-center study to determine the recommended dose of the chimeric antigen receptor T-cell treatment CYAD-211 after a non-myeloablative preconditioning chemotherapy in multiple myeloma patients with relapsed or refractory disease
The purpose of the study is to determine the safety and tolerability of the investigational product CYAD-211 when administered as a single infusion after a ...Phase
Interventional
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A Multicenter Double-Blind Randomized Placebo-Controlled Parallel Group Study with Open-Label Extension Phase of Lorcaserin as Adjunctive Treatment in Subjects with Dravet Syndrome
The purpose of this study is to assess the safety (symptoms and medical problems you may experience –known as side effects) and efficacy (how well ...Phase
Interventional
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HOPE Consortium Trial to Reduce Pain and Opioid Use in Hemodialysis
The primary objective is to evaluate the effectiveness of pain coping skills training compared with usual care for reducing pain interference (primary outcome), and for ...Phase N/A Interventional
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Port Delivery System with Ranibizumab in patients with Diabetic Retinopathy with or without Diabetic Macular Edema
The purpose of this study is to compare the effects, good or bad, of ranibizumab when it is delivered by an ocular (eye) implant (also ...Phase
Interventional
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Platelet and Endothelial Dysfunction in Psoriasis
The purpose of this study is to investigate blood vessel wall function, platelet (involved in clotting) activity, risk of heart disease measurements, and genetic information ...Phase N/A
Non-Interventional
Accepts Healthy Volunteer
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A single-center observational study of the relationship between sleep synovial fluid cytokine profiles & outcomes of ACL reconstruction
The purpose of this study is to see if there is a relationship between sleep around the time of surgery and outcomes of anterior cruciate ...Phase N/A Non-Interventional
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A Double-blind Randomized Placebo-controlled Multicenter Study to Assess the Effect of Omecamtiv Mecarbil on Exercise Capacity in Subjects with Heart Failure with Reduced Ejection Fraction and Decreased Exercise Tolerance
The purpose of this study is to find out more about the effects of an investigational drug called omecamtiv mecarbil (OM), when given to people ...Phase
Interventional
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Electrical stimulation of cochlear nucleus for hearing restoration
The study examines hearing and sound perception in deaf individuals who are treated with cochlear implants or auditory brainstem implants (ABIs). The goal is to ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
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A Phase 1b Study of Nivolumab in Patients with Autoimmune Disorders and Advanced Malignancies (AIM-NIVO)
We want to know the safety and tolerability of the anti-programmed death 1 (PD-1) antibody nivolumab at different dose levels for patients with autoimmune disorders ...Phase
Interventional
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A Phase 1/2 Open-Label Rolling-Arm Umbrella Platform Design of Investigational Agents With or Without Pembrolizumab or Pembrolizumab Alone in Participants with Melanoma (KEYNOTE-U02): Substudy 02A
The purpose of the study is to determine the safety and tolerability of investigational treatment combinations with or without pembrolizumab or pembrolizumab alone for the ...Phase
Interventional
