Displaying 647 (all) recruiting clinical trials.
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Cerliponase alfa Observational Study
This is a, multicenter, observational study for patients with a confirmed diagnosis of neuronal ceroid lipofuscinosis type 2 (CLN2 disease), also known as TPP1 deficiency ... -
Distal Ischemic Stroke Treatment with Adjustable Low-profile Stentriever
Stroke is a condition where the blood flow to the brain is blocked, potentially resulting in lack of oxygen, brain damage and loss of function ... -
The Lifestyle Intervention in Fibroid Elimination Program (LIFE)
This prospective cohort pilot study will enroll asymptomatic, post-surgical patients who underwent a laparoscopic, open, robotic myomectomy, or other procedure ie Sonata, Accessa for fibroid ... -
A multi-cohort randomized Phase 2 open-label study to assess the preliminary efficacy safety and pharmacokinetics of BIVV020 for prevention and treatment of antibody-mediated rejection in adult kidney transplant recipients.
Antibody-mediated rejection (AMR) remains as the most common cause of allograft failure following kidney transplantation. AMR leads to complement-induced inflammation and endothelial injury of the ... -
Screening Assessment of Overlap Spondyloarthritis in Patients with Inflammatory Bowel Disease
Despite the known prevalence of Spondyloarthritis (SpA) in patients with Inflammatory Bowel Disease (IBD), a formalized screening and disease activity monitoring strategy is not routine ... -
Identification of Skin Injuries in Patients with Dark Skin Tones ?
This study will be a prospective, observational cohort study conducted over a 12-month period on a sample of acute and critically ill patients (>18 years ... -
A Phase 3 Randomized Double-Blind Placebo-Controlled Study to Evaluate the Efficacy and Safety of Deucravacitinib in Participants with Active Systemic Lupus Erythematosus (POETYK-SLE-2)
This study is a double-blinded 52-week clinical trial to evaluate the efficacy and safety of deucravacitinib in adult participants with active Systemic Lupus Erythematosus (SLE ... -
A Phase 1/2 Open-Label Study to Evaluate the Safety Tolerability Pharmacokinetics and Efficacy of TNG260 as Single Agent and in Combination with an anti-PD-1 Antibody in Patients with STK11-Mutated Advanced Solid Tumors
This study is testing a new drug called TNG260 (a specific medicine referred to as a CoreDAC inhibitor that can undo the way the immune ...
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A Phase 1 Open-Label Multi-Center Safety and Efficacy Study of PRT3789 in Participants with Select Advanced or Metastatic Solid Tumors with a SMARCA4 Mutation
This is a study to test a new drug called PRT3789 for safety and effectiveness in treating certain types of advanced or metastatic solid tumors ...
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Phase 1b/2a Study of Gemcitabine and Nab-paclitaxel in Combination with VS-6766 and Defactinib in Patients with Previously Untreated Metastatic Adenocarcinoma of the Pancreas
This study is about testing a combination of drugs (gemcitabine, nab-paclitaxel, VS-6766, and defactinib) to treat a type of cancer called pancreatic ductal adenocarcinoma (PDAC ...