Displaying 743 (all) recruiting clinical trials.
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A Phase 1b/2 Study of Immune and Targeted Combination Therapies in Participants With RCC (U03): Substudy 03B
The purpose of the study is to evaluate the safety, tolerability and efficacy of 1 or more experimental arms for the treatment of advanced renal ...Phase
Interventional
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Oral Nutritional Optimization in Total Joint Arthroplasty
The purpose of this study is to investigate whether giving patients nutritional supplements both before and after surgery could have an effect on changes in ...Phase N/A Interventional
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A One Year Observational Investigation of Subjects with Open Angle Glaucoma And a Documented History of Progressive Visual Field Loss
The purpose of this study is to examine which ophthalmic measures routinely used in eye doctor’s offices can find changes in glaucoma the earliest ...Phase N/A
Non-Interventional
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A Phase 1 Open-Label Safety Pharmacokinetic and Preliminary Efficacy Study of STRO-002 an Anti-Folate Receptor Alpha (FolRa) Antibody-Drug Conjugate (ADC) in Patients With Advanced Epithelial Ovarian Cancer (Including Fallopian Tube or Primary Peritoneal Cancers) and Endometrial Cancers
The purpose of the study is to determine the safety and efficacy of STRO-002, which is a antibody drug conjugate (ADC) given intravenously every 3 ...Phase
Interventional
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Psychological Impact of Covid-19 on Postpartum Period of Parous Mothers: A Retrospective Case Series
The purpose of this research study is to assess the impact of COVID on postpartum wellbeing. This research study is being done to collect the ...Phase N/A Non-Interventional
Accepts Healthy Volunteer
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Photobiomodulation Therapy Using the MuReva Phototherapy System to Demonstrate Safety and Reduce the Incidence of Oral Mucositis in Adult Patients with Head and Neck Cancer Receiving Concurrent Radiation and Chemotherapy
The overall purpose of this clinical study is to evaluate safety and efficacy of the MuReva Phototherapy System with a light delivery mouthpiece to reduce ...Phase N/A Interventional
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A randomized double-blind placebo-controlled Phase 3 study of Debio 1143 in combo w/ platinum-based chemo & standard fractionation intensitymodulated radiotherapy in patients w/ locally advanced HNSCC suitable for definitive chemoradiotherapy
The purpose of the study is to compare the efficacy and safety of Debio 1143 versus matched placebo, when administered in combination with platinum-based chemotherapy ...Phase
Interventional
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AALL1821: A Phase 2 Study of Blinatumomab (NSC# 765986 IND# 125462) in Combination with Nivolumab (NSC# 748726 IND# 125462) a Checkpoint Inhibitor of PD-1 in B-ALL Patients Aged >/=1 to
The purpose of the study is to investigates how well nivolumab when given together with blinatumomab work compared to blinatumomab alone in treating patients with ...Phase
Interventional
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A multipart exploratory study to evaluate splenic nerve stimulation in patients with rheumatoid arthritis.
The purpose of this research study is to test an investigational device and its accessories to help determine whether this study device may be used ...Phase N/A Interventional
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A Phase 1 Open-label Preliminary Pharmacokinetics (PK) and Safety Study of CLN-049 (An fms-like tyrosine kinase 3 [FLT3] x cluster of differentiation 3 [CD3] bispecific T cell engager) in Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML)
The purpose of the study is to determine the safety and tolerability of intravenous (IV) administered CLN-049. CLN-049 is a novel BITE therapy that target ...Phase
Interventional
